Examples of 'transactivation' in a sentence
Meaning of "transactivation"
The process by which a protein enhances gene expression
Show more definitions
- The activation of something by another entity that has a spatial relationship with it
- The activation of a gene by the presence of another at a different locus, especially following infection by a virus
How to use "transactivation" in a sentence
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transactivation
Transactivation test is used as a primary screening test.
The process of stimulation of transcription is called transactivation.
Transactivation assay was used as a primary screening test.
The art is in need of compounds that antagonize transactivation.
Background level is transactivation in the absence of an added ligand.
The art is in need of compounds that induce transactivation.
Tat transactivation is reflected by increased expression of firefly luciferase.
This induction of transcription is termed transactivation.
High levels of transactivation were seen in all three cell lines.
This mechanism is referred to as transactivation.
This transactivation has been.
It was observed that none of these clones exhibited any transactivation.
A description of the holoreceptor transactivation assay is also provided below.
This activation of genes by an activator protein is often called transactivation.
The heterologous polypeptide may be a transactivation domain of a transcription factor.
See also
Chimeric proteins can be further modified by addition or subtraction of transactivation domains.
These mutants lacked transactivation activity and retained transrepression activity.
Stimulation is through transactivation.
This example describes a transactivation assay for determining PPARalpha modulating activity.
Another type of modulator is one that induces both transrepression and transactivation.
Another type of modulator of is one that induces transactivation without inducing transrepression.
Another type of modulator is one that antagonizes a modulator that induces transactivation.
Dexamethasone induced transactivation in both the mutants and the wild type protein.
It does not rely on transactivation.
These undesirable additional transactivation effects are surprisingly substantially avoided in accordance with the present invention.
This experiment clearly shows that there is transactivation of the hCMV promoter.
A dissociated compound is a modulator that induces transrepression while inducing none or minimal transactivation.
The bottom panel shows that luciferase transactivation does not occur in the presence of tetracycline.
Most of these consequences are attributed to the transactivation of GR.
The transactivation activity was evaluated using the protocol described by Kittiworakam et al.
However RARa appears as the predominant receptor for the transactivation in the HeLa cells.
Transactivation is the process by which a GPCR activates a growth factor receptor.
The Tat component may be a transactivation mutant.
SHP inhibits transactivation potential of superfamily members with which it interacts.
CAT activity was used as a measure of transactivation.
Maximal levels of transactivation were observed after a five minute exposure to Tat.
The identification of PPARY agonists is done by a specific transactivation assay in eukaryotic cells.
This is an example of a transactivation assay for determining PPAR gamma modulating activity.
These results indicate that opioids induce VEGF receptor transactivation.
Allowing the compound to suppress Tat transactivation of the lentivirus in the cell.
This normally nuclear protein tetramerizes to bind DNA and regulate transactivation.
The cellular cofactors required for the transactivation of HIV are present in the HeLa cells.
The Tat in this plasmid contains three mutations to inactivate the transactivation function.
There was also no transactivation observed with the Tat Bru derivative possessing the carboxymethylated cysteines.
Cumate addition abrogates DNA binding and therefore transactivation by cTA.
Compounds that reduce the transactivation by Avandia are PPAR partial agonists.
Other cell lines were also tested for Tat uptake and transactivation activity.
PPAR Transactivation activity for selected compounds.
CREB phosphorylation is a crucial process to allow the transactivation of the viral promoter.
This transactivation was inhibited by Galangin and BACE inhibitor IV.
