Examples of 'translocation domain' in a sentence
Meaning of "translocation domain"
translocation domain: In biology, a translocation domain refers to a specific region of a protein that is involved in moving molecules from one place to another within a cell or organism
How to use "translocation domain" in a sentence
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translocation domain
The translocation domain functions as follows.
The toxin was preferably one with a translocation domain to facilitate uptake into a cell.
The translocation domain is the HN domain of a clostridial neurotoxin.
A random coil belt extends from the botulinum type A translocation domain and encircles the light chain.
The translocation domain.
In other embodiments, the eptiope resides in the translocation domain of tcdA.
The translocation domain can include the entire sequence of domain II.
Optionally, an adjuvant or one or more translocation domain may be further provided.
The Translocation Domain is obtained from a bacterial or viral protein source.
Therefore, in one embodiment of the invention the immunoconjugate does not comprise a translocation domain.
An example for a translocation domain is domain II from Pseudomonas aeruginosa exotoxin A.
Fusion proteins comprising a non-cytotoxic protease, a targeting moiety, a protease cleavage site and a translocation domain.
Translocation Domain source.
A polypeptide according to any preceding claim, wherein the translocation domain comprises a clostridial neurotoxin translocation domain.
The translocation domain may itself perforate membranes, thus having toxic or insecticidal properties.
See also
The LacS protein is composed of a translocation domain and a regulatory domain ( IIA ).
The translocation domain sequence of Pseudomonas aeruginosa is well known and is represented by,.
Typically, the cytotoxic A domain must be escorted to the cytoplasm by a translocation domain.
Therefore, the protein contains the translocation domain and the catalytic domain of IT.
The botulinum neurotoxin of the present invention also comprises a toxin translocation domain ( HN ).
The pCR 4 vector encoding the diphtheria translocation domain is cleaved with Nhe I and Xbal.
Alternatively, a Clostridial toxin HCN translocation facilitating domain may be combined with a non-clostridial translocation domain peptide.
And the modified Pseudomonas aeruginosa translocation domain ( helix F deletion ) SEQ.
Alternatively, a Clostridial toxin HCN translocation facilitating domain may be combined with a non-clostridal translocation domain peptide.
The method of claim 15, wherein the translocation domain comprises a clostridial neurotoxin translocation domain.
The cleavage site is located between the L-chain and the translocation domain components.
In one embodiment, the translocation domain is a HN domain ( or a fragment thereof ) of a clostridial neurotoxin.
The anti-inflammatory compound of claim 16, wherein the membrane translocation domain facilitates membrane translocation in vivo.
Translocation Domain PE-like chimeric immunogens also comprise an amino acid sequence encoding a " PE translocation domain . ".
A polypeptide according to any of Claims 7-9, wherein the translocation domain comprises a clostridial neurotoxin translocation domain.
The translocation domain of BoNT / A ( Tm ) was expressed and produced using a synthetic gene.
Another useful targeting molecule is the translocation domain of a Pseudomonas exotoxin A ( ETA ), e.
No. 53 and the translocation domain from Pseudomonas aeruginosa SEQ.
Alternatively, the Translocation Domain may be of a non-clostridial origin.
Alternatively, the Translocation Domain may be of a non-clostridial origin ( see Table 4 ).
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The first of three types of translocation is introduction
Today translocation of the site has ended
Theoretical studies of proton translocation in membrane proteins
