Examples of 'treprostinil' in a sentence
Meaning of "treprostinil"
Treprostinil is an adjective used to describe a synthetic analog of prostacyclin that is used to treat pulmonary arterial hypertension
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- An analog of the biological compound prostacyclin, used in the treatment of hypertension.
How to use "treprostinil" in a sentence
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treprostinil
Treprostinil monohydrate can be formulated prior to administration.
Both SAEs were judged unlikely to be related to treprostinil.
Treprostinil administration using a metered dose inhaler.
Synthesis of intermediate for treprostinil production field.
Subsequent examples investigated higher concentrations of treprostinil.
Treprostinil can be administered subcutaneously as supplied.
It is not known whether treprostinil is excreted in breast milk.
Data has been generated to characterize a monohydrate form of treprostinil.
The insulin and treprostinil are present in a fixed dose combination.
All patients received subcutaneous treprostinil.
The treprostinil monohydrate was prepared according to the following procedure.
Process for the preparation of treprostinil and derivatives thereof.
Treprostinil infusion was not discontinued during the laproscopic procedure.
A significant difference in the reactivity of various esters of treprostinil was observed.
Treprostinil is a synthetic analogue of prostacyclin.
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The present description relates to a novel monohydrate form of treprostinil.
Treprostinil monohydrate can be stored and shipped with no special handling.
Disclosed herein is insulin for use in combination with treprostinil.
The anhydrous or wet treprostinil being recrystallized may have a range of purity.
The present invention relates to a novel monohydrate form of treprostinil.
No serious adverse events attributed to treprostinil occurred during the trial.
The composition includes human insulin or an insulin analog and treprostinil.
The major effects of treprostinil are vasodilation of arteries in the lungs and body.
Changes in secreted cytokines were also observed as a result of treprostinil exposure.
The description relates to treprostinil monohydrate prepared according to the aforementioned process.
These side effects were resolved generally by decreasing the treprostinil dose.
It has now surprisingly been found that treprostinil can exist in a monohydrate form.
Unmodified treprostinil is released by hydrolytic cleavage of the linker under physiological pH and temperature.
Patients were observed for at least two hours following the initiation of treprostinil therapy.
One embodiment of the invention is treprostinil monohydrate prepared according to the aforementioned process.
Treprostinil is of high metabolic stability which specifically allows for administration by various routes.
Caution is advised when administering treprostinil to patients who have impaired kidney or liver function.
Treprostinil provided pain relief in all patients as well as wound healing in three patients.
Process for the preparation of treprostinil monohydrate and its use for storage and shipping.
The other side effects associated with epoprostenol can also occur in patients treated with treprostinil.
Treprostinil is also currently unavailable for use in Brazil.
Study design to evaluate the effects of treprostinil on MSC activity.
Administration of Treprostinil or its derivatives treats neuropathic diabetic foot ulcers.
Also disclosed in these publications are processes and intermediates useful for the preparation of Treprostinil.
Both treprostinil and iloprost are approved for inhaled delivery in PAH.
In one embodiment of the present invention the Treprostinil analogue is an isomer of Treprostinil.
Addition of treprostinil also led to increases in insulin Cmax compared to Humalog alone.
The physiologically acceptable salts of Treprostinil include salts derived from bases.
The Treprostinil therapy also reduces pain and disability associated with DIL.
This example demonstrates that high levels of treprostinil negatively impacted cellular viability of MSC.
In sum, treprostinil is of great importance from a medicinal point of view.
Chemical testing results for treprostinil in BWFI.
The stability of treprostinil was monitored by a fully validated stability indicating HPLC assay.
In addition to instability, the anhydrous treprostinil is difficult to handle.
The administration of Treprostinil treats and prevents foot ulcers in patients with diabetic neuropathy.