Examples of 'unnatural amino acid' in a sentence
Meaning of "unnatural amino acid"
unnatural amino acid: This phrase is used in biochemistry to refer to amino acids that are not typically found in proteins and may have been chemically modified
How to use "unnatural amino acid" in a sentence
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unnatural amino acid
An analog may include an unnatural amino acid.
The unnatural amino acid may be modified to incorporate a chemical group.
The amino acid may be an unnatural amino acid.
The unnatural amino acid may be modified to incorporate a ketone group.
It also is useful to include an unnatural amino acid in the chelator.
The unnatural amino acid may be incorporated into the polypeptide.
Represents the side chain of a natural or unnatural amino acid.
Unnatural amino acid polypeptide compositions can also be administered vÃa liposomes.
The amino acid may be a natural or an unnatural amino acid.
Access to unnatural amino acid building blocks via asymmetric hydrogenation or biocatalysis.
The spacer may be any naturally occurring or unnatural amino acid.
A natural or unnatural amino acid is the starting point for the scheme.
The first linker may be attached to a ketone of the unnatural amino acid.
Any unnatural amino acid may be used in accordance with the disclosure.
Relaxin polypeptides comprising at least one unnatural amino acid are dislcosed herein.
See also
The unnatural amino acid may replace an amino acid of the polypeptide.
Relaxin polypeptides comprising at least one unnatural amino acid are provided in the invention.
Such unnatural amino acid residues are well known to one skilled in the art.
Proteins or polypeptides of interest with one unnatural amino acid are a feature of the invention.
The unnatural amino acid may be inserted into the heavy chain of the antibody.
These pairs can be used to incorporate an unnatural amino acid into growing polypeptide chains.
The unnatural amino acid may be inserted into the light chain of the antibody.
The cell uses the components to incorporate the unnatural amino acid into a growing polypeptide chain.
The unnatural amino acid may react with the linker to create a chemical bond.
The TLD may comprise a polypeptide comprising the unnatural amino acid.
The addition of the unnatural amino acid did not affect the growth rate of cells.
The Amber mutant site allows for the incorporation of an unnatural amino acid.
Aa is a natural or unnatural amino acid residue ;.
An unnatural amino acid that comprises a saccharide moiety ;.
The linker may be connected to the unnatural amino acid within the TLD.
An unnatural amino acid comprising a trans-cyclooctenyl group of the formula, wherein.
The TLD may comprise an unnatural amino acid.
Rx is a natural or unnatural amino acid side-chain group that is capable of crosslinking ;.
Compositions, which include proteins that include an unnatural amino acid are also disclosed.
In some embodiments, the unnatural amino acid is incorporated into the polypeptide in vivo.
In one embodiment, the kit further includes at least one unnatural amino acid.
Incorporating the unnatural amino acid into the protein comprises,.
The term " amino acid " as used herein refers to any natural or unnatural amino acid.
The unnatural amino acid may be incorporated into the non-antibody based polypeptide.
In certain embodiments of the methods, the protein comprising an unnatural amino acid is sulfo-hirudin.
Thus, this type of unnatural amino acid can be viewed as a natural amino acid derivative.
The spacer may be, for example, a residue of any naturally occurring or unnatural amino acid.
And with a second unnatural amino acid comprising a cyclooctynyl group of the formula, wherein.
When expressed, this mutagenized nucleic acid encodes a polypeptide comprising one or more unnatural amino acid.
The unnatural amino acid may replace an amino acid of the non-antibody based polypeptide.
Example 3 Addition of molecules to proteins with an unnatural amino acid.
For example, the unnatural amino acid may replace a serine residue of the antibody light chain.
FIG . 1 provides the chemical structure of the unnatural amino acid sulfotyrosine.
A list of unnatural amino acid contemplated herein is shown in Table 2.
This provides an O-RS that preferentially aminoacylates the O-tRNA with the unnatural amino acid.
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