Examples of 'upar' in a sentence
Meaning of "upar"
upar (noun): A term used in South Asia, particularly in Hindi, to refer to the upper or higher regions of a place
How to use "upar" in a sentence
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upar
Specificity for uPAR was confirmed by western blotting.
Soluble forms thereof are known as soluble uPAR.
First the region of uPAR inducing chemotaxis was identified.
This would be an example of a uPAR activity.
It is well known that uPAR is implicated in numerous biological functions.
Western blot analysis was performed using an antibody specific for uPAR.
It was also determined whether uPAR levels were influenced by exercise.
Thus uPAR seems to be an important player in the regulation of this process.
The chemotactic activity of uPAR has many of the properties of chemokines.
All of these phenomena are blocked by blocking the access of uPA to uPAR.
In these cases the uPAR antibody weakly labelled singular neurons.
The epitopes recognized by these mAbs are peptide regions within uPAR.
It is a long time that uPA and uPAR are known to be involved in inflammation.
The data also indicate that uPA directly cleaves uPAR.
Discusses the biological significance of uPAR in the glioblastoma invasión process.
See also
Extensive uPAR expression was found in kidneys treated with suPAR protein delivery.
This activation could be blocked by specific inhibitors uPAR blocking antibody or cycloRGDfV.
The expression of uPA and uPAR are typically greater in more aggressive forms of disease.
Is a panel of immunostaining images and bar graphs showing uPAR mediates podocyte migration.
It has been shown that uPAR directly binds vitronectin and promotes cell adhesion.
This interaction results in the simultaneous knockdown of uPA and uPAR gene expression.
Adhesion and migration require only uPAR occupancy but not uPA catalytic activity.
The subject is to be injected with the molecule having binding specificity for uPAR.
Knockdown of uPA and uPAR expression by RNAi inhibits cell proliferation and induces apoptosis.
Is a chart showing the correlation between the suPAR level and the uPAR level.
The tumour tissue has previously been shown to express high levels of uPA and uPAR.
The disclosure further provides diagnostic methods using the uPAR antibodies of the disclosure.
The proteolytic cleavage of uPAR from the cell surface releases a chemotactic active form of suPAR.
The antibodies can also downregulate the number of uPAR molecules on the cell membrane.
The level of uPAR increases during disease progression in transgenic ALS mice.
The mAbs made by this process may or may not bind free uPAR in solution.
UPA and its receptor uPAR are involved in tumor invasión and metastasis.
Is a panel of immunostaining images and graphs showing stable knockdown of uPAR mRNA using siRNA.
All blood donors had measurable uPAR receptor on the PBMC and measurable suPAR in serum.
The construct consists of a human CMV promoter and homologous sequences targeted against uPA and uPAR.
HeLa cells express abundant amounts of uPAR but do not express uPA.
Cathepsin B and uPAR siRNA suppresses intracranial tumor growth.
The Antibody Approach The present inventors have generated a panel of mAbs targeting uPAR.
Effect of pCU vector on cathepsin B and uPAR protein levels in total cell extracts.
Alternatively, uPAR is released / secreted from the cell surface without proteolysis.
In another embodiment, the antibody that binds uPAR is labeled.
Cathepsin B and uPAR have been shown to play significant roles in ECM degradation.
In another preferred embodiment, a mimetic of a uPAR ligand binds to uPAR.
Schematic depiction of uPAR in complex with avB3 integrin and vitronectin.
In another example, an agent directly inhibits binding of uPAR to its ligand.
No current methods measuring uPAR is capable of this non-invasively in humans.
Since uPAR is itself a membrane protein, it may not require a presentation molecule.
The same mechanism applies to uPA binding to the surface-anchored uPAR.
Furthermore, when uPAR was inhibited in laboratory experiments, bradykinin levels also decreased.
For example, regulatory regions would be a target to decrease the expression of uPAR.
