Examples of 'upregulation' in a sentence
Meaning of "upregulation"
Upregulation refers to the process of increasing the number of receptors on the cell surface, leading to an increase in cellular response to a stimulus
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- The process, in the regulation of gene expression, in which the number, or activity of receptors increases in order to increase sensitivity
How to use "upregulation" in a sentence
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upregulation
Counteracting this upregulation decreases depressive symptoms.
Upregulation of gene expression can range from slight to substantial.
Downregulation and upregulation in drug addiction.
No upregulation in these genes was observed in control mice.
The overall result is an upregulation of the immune system.
The upregulation of GcgR was not statistically significant.
Numbers in bold print represent an upregulation of the mRNA.
This specific upregulation is linked to neuronal regeneration.
During the period of upregulation.
This involves upregulation of various proteases.
Gene amplification is a common mechanism leading to upregulation of gene expression.
No or only little upregulation was seen in the other lymphoma samples.
Each cytokine when given alone is inadequate for optimal upregulation.
This protocol resulted in significant upregulation of definitive endoderm markers.
Upregulation and downregulation can also happen as a response to toxins or hormones.
See also
The reduction subsequently leads to upregulation of ACh expression in the brain.
Upregulation of target genes can also render the fungicide ineffective.
Experimental and clinical studies showed upregulation of ras after menopause.
This upregulation was observed in PBMCs of one out of two donors tested.
Lesions were preceded by the expression and progressive upregulation of proinflammatory molecules.
This upregulation may facilitate endogenous neurorepair in the ischemic brain.
A highly logical pattern appeared to drive the clustered upregulation of these genes.
Upregulation refers to the increase in the number of receptor sites on the membrane.
This effect coincided with an upregulation of the expression of several neural markers.
Its upregulation has been shown to cause premature aging in hematopoietic stem cells.
The degree of functional impairment is roughly correlated with magnitude of sympathetic upregulation.
Upregulation in stress.
This is further evidenced by upregulation of versican gene observed after vascular injury.
Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice.
This effect was related to an upregulation of the respiratory innate and specific immune responses.
Upregulation of the Wnt pathway influences that differentiation as is disclosed in the examples.
This resulted in strong upregulation of Langerin expression.
This upregulation response in vitro correlates with the in vivo immunogenicity of peptides.
This protocol resulted in significant upregulation of DE markers.
This is mediated by upregulation of the proteolysis and downregulation of protein synthesis in muscle.
Angiotensin II induces vasoconstriction and inflammation via upregulation of cytokines and chemokines.
This upregulation is confined to the vascular endothelial cells in close proximity to the tumor.
Endogenous retinal growth factor mRNA upregulation was determined by Northern blot analysis.
It shows upregulation in ovary tumours from two patients and in one stomach tumour sample.
PSMA transcripts were detected in all prostate specimens with upregulation in a subset of malignancies.
Also preferred is upregulation of genes encoding enzymes involved in the pentose phosphate pathway.
This cytoprotection to drug toxicity has been linked to a VEGF mediated upregulation of survivin expression.
Iron is necessary for the upregulation of transcriptional elements for cell replication and repair.
Increases in BAT temperature are indicative of an upregulation of thermogenesis in BAT.
This was accompanied by upregulation of the glutathione level and reduced reactive oxygen species generation.
It was observed that loading with STAPPAHGV led to a higher upregulation of HLA.
The graphs depict fold upregulation over the lowest data point in the data set.
Downregulation and Upregulation.
This hypoxia induced upregulation of VEGF can be inhibited pharmacologically.
A " change in gene expression " refers to detection of upregulation or downregulation.
