Examples of 'valdecoxib' in a sentence
Meaning of "valdecoxib"
Valdecoxib is an adjective that may describe a substance or product related to a specific pharmaceutical compound or ingredient
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- A nonsteroidal anti-inflammatory drug formerly used to treat osteoarthritis, rheumatoid arthritis, and menstrual pain.
How to use "valdecoxib" in a sentence
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valdecoxib
It is not known whether valdecoxib is excreted in human milk.
Parecoxib is rapidly hydrolysed to the active metabolite valdecoxib.
Valdecoxib is not removed by haemodialysis.
This means that it is converted to valdecoxib in the body.
Valdecoxib for use in the present invention may be a free form or a pharmaceutically acceptable salt.
Combination therapy of radiation and valdecoxib for the treatment of neoplasia.
Exposure of a parecoxib composition to moisture tends to cause significant conversion of parecoxib to valdecoxib.
For valdecoxib appropriate doses can be selected by reference to the patent literature cited hereinabove.
Parecoxib is a prodrug of valdecoxib.
The Valdecoxib has a phenylsulfonamide moiety with a central isoxazole ring.
Effects of other medicinal products on the pharmacokinetics of parecoxib or its active metabolite valdecoxib.
Valdecoxib is not currently available in the United States.
Plasma Cl for valdecoxib.
The data on valdecoxib and parecoxib presented in the CABG Coronary Artery Bypass.
The following calculated plasma pharmacokinetic parameters for valdecoxib are given in Table 1,.
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Valdecoxib will be a limited use benefit for the following conditions,.
Steady state plasma concentrations of valdecoxib were reached within 4 days with twice daily dosing.
Valdecoxib also is approved for the relief of pain of menstrual cramps ( primary dysmenorrhea ).
The volume of distribution of valdecoxib after its IV administration is approximately 55 litres.
Valdecoxib is eliminated via hepatic metabolism with less than 5 % unchanged valdecoxib recovered in the urine.
Parecoxib converts to the substantially water-insoluble selective COX-2 inhibitory drug valdecoxib following administration to a subject.
Valdecoxib was also used off-label for controlling acute pain and various types of surgical pain.
O Unoprostone, ses seis et dérivés Valdecoxib and its salts.
Valdecoxib blood plasma concentration was determined using a validated high performance liquid chromatography ( HPLC ) procedure.
Examples of COXIB-irihibitors include but are not limited to, rofecoxib, celecoxib, etoricoxib, valdecoxib and melotican.
The data on valdecoxib and parecoxib presented in the CABG (Coronary Artery Bypass Graft) and.
In still another embodiment, the cyclooxygenase-2 inhibitor is Valdecoxib.
Valdecoxib is a selective COX-2 inhibitor within the clinical dose range.
The process of Claim 1 wherein the selective cyclooxygenase-2 inhibitory drug is valdecoxib.
Valdecoxib is a NSAID with potent inhibitory action specific to COX-2.
The sulfonamide drug for use according to the invention is a selective COX-2 inhibitory drug, valdecoxib.
In humans, studies demonstrated that valdecoxib metabolism is predominantly mediated via CYP3A4 and 2C9 isozymes.
Based on molecular weights, complete conversion of 1 mg parecoxib produces about 0.85 mg valdecoxib.
Valdecoxib is a selective cyclooxygenase-2 ( COX-2 ) inhibitor within the clinical dose range.
Among those, rofecoxib, celecoxib, etoricoxib, valdecoxib and lumiracoxib.
Useful NSAIDs include ibuprofen, indomethacin, naproxen, aspirin, acetominophen, celecoxib and valdecoxib.
After intravenous or / m administration of parecoxib sodium T1 / 2 valdecoxib - about 8 hours.
The active substance in Dynastat, parecoxib, is a ‘ prodrug ' of valdecoxib.
Cox-II inhibitors include, but are not limited to, rofecoxib, celecoxib, and valdecoxib.
COX inhibitors include, for example, aspirin, celecoxib, rofecoxib, and valdecoxib.
Therefore, particularly preferred COX-2 inhibitors include rofecoxib, celecoxib, and valdecoxib.
Exemplary COX-2 inhibitors include, but are not limited to, celecoxib, rofecoxib and valdecoxib.
Nonlimiting examples of COX-2 inhibitos include, celecoxib, etoricoxib, parecoxib, rofecoxib, valdecoxib and lumiracoxib.
