Examples of 'variant protein' in a sentence
Meaning of "variant protein"
variant protein - The term refers to a modified form of a protein resulting from genetic variations or mutations. It is commonly used in the field of biology or biochemistry to describe proteins with altered amino acid sequences
How to use "variant protein" in a sentence
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variant protein
Also contemplated are variant protein complexes of the invention.
An analog is an example of a variant protein.
The Fc variant protein may have ligand relative to a comparable molecule.
The desired polynucleotide encoding the RS variant is used to generate the RS variant protein.
The variant protein may be expressed from an isolated DNA sequence encoding the variant protein.
A nucleic acid encoding a variant protein according to claim 1.
The Fc variant protein may have enhanced binding to an Fc receptor.
Obtaining a parent polynucleotide encoding one or more variant protein motifs ;.
The Fc variant protein may have reduced binding to an Fc receptor.
Also encompassed are the nucleotide sequence ( s ) encoding the variant protein or polypeptide.
An Fc variant protein may have reduced ADCC activity relative to a comparable molecule.
In a specific embodiment, the Fc variant protein has enhanced binding to an Fc receptor.
An Fc variant protein may have enhanced CDC activity relative to a comparable molecule.
In a specific embodiment, the Fc variant protein has reduced binding to an Fc receptor.
A variant protein according to para 18 wherein said engineered glycoform improves effector function.
See also
For example, transgenic AHAS variant protein containing plants can be cultivated.
A variant protein according to para 1 wherein said Fc variant further comprises an engineered glycoform.
Where the herbicide is an imidazolinone herbicide, the herbicide resistant AHAS variant protein preferably has,.
The Fc variant protein may have enhanced binding to the Fc receptor FcYRIIIA.
Suitably, the CD38 CAR or the TRAIL variant protein are encoded by a polynucleotide.
The Fc variant protein may have reduced binding to the Fc receptor FcYRIIIA.
ERFE+12 is translated into a functional variant protein in SF3B1MUT erythroblasts.
The Fc variant protein may have reduced binding to the Fc receptor FcRn.
The dimeric protein of claim 5, wherein the IL-2 variant protein comprises the N88R substitution.
However, variant protein fragments may also be prepared by in vitro synthesis.
In one embodiment, an Fc variant protein has reduced ADCC activity relative to a comparable molecule.
A variant protein according to para 21, wherein said effector function is ADCC.
In one embodiment, an Fc variant protein has enhanced ADCC activity relative to a comparable molecule.
A variant protein according to para 21 wherein said effector function is ADCP.
In one embodiment, an Fc variant protein has enhanced CDC activity relative to a comparable molecule.
A variant protein according to para 25 or 29 wherein CDC is unaffected.
In one embodiment, the Fc variant protein has enhanced serum half-life relative to comparable molecule.
A variant protein according to para 25 or 29 wherein CDC is ablated.
In some embodiments, a variant protein is " truncated " with respect to a reference, full-length protein.
Variant Protein C zymogen contains a mutation PC ( R15Q ), that prevents activation of the molecule.
The Fc variant protein may have enhanced binding to C1q relative to a comparable molecule.
This variant protein is reported to have a longer half-life than the native protein C.
The IL-3 variant protein secreted into the medium can be recovered by standard biochemical approaches.
The Fc variant protein may have enhanced serum half-life relative to comparable molecule.
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Examples of using Variant
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The first variant of the second sentence
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