Examples of 'vigabatrin' in a sentence
Meaning of "vigabatrin"
vigabatrin (noun): Vigabatrin is a medication used to treat epilepsy. It works by reducing the amount of certain chemicals in the brain that can cause seizures
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- An anticonvulsant drug C₆H₁₁NO₂ that inhibits enzymatic degradation of gamma-aminobutyric acid.
How to use "vigabatrin" in a sentence
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vigabatrin
Amended for vigabatrin containing medicinal products.
There is no specific antidote for vigabatrin overdose.
Detection of vigabatrin attributed visual field defects.
The overall safety profile of vigabatrin was reviewed.
Vigabatrin can cause permanent vision loss.
Breastfeeding is not recommended during vigabatrin treatment.
Vigabatrin generally is well tolerated in young children.
Corresponding results were also obtained using vigabatrin.
Hypersensitivity to vigabatrin or to any excipient in the medicinal product.
Psychiatric reactions have been reported during vigabatrin therapy.
Vigabatrin is excreted into breast milk.
The retinal toxicity of vigabatrin can be attributed to a taurine depletion.
Vigabatrin should be gradually withdrawn under close medical supervision.
The sedative effect of vigabatrin decreases with continuing treatment.
Vigabatrin should only be used during pregnancy if clearly necessary.
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The effectiveness of hemodialysis in the treatment of vigabatrin overdose is unknown.
Vigabatrin overdose has been reported.
Food administration does not alter the extent of vigabatrin absorption.
Vigabatrin is an antiepileptic drug with a clearly defined mechanism of action.
The effectiveness of haemodialysis in the treatment of vigabatrin overdose is unknown.
Vigabatrin is not significantly metabolized.
It is usually detected after months or years of treatment with vigabatrin.
Studies with vigabatrin revealed no evidence of mutagenic or carcinogenic effects.
The active substance is vigabatrin.
The effect of dialysis on vigabatrin clearance has not been adequately studied.
The onset is usually after months to years of vigabatrin therapy.
Vigabatrin should not be used concomitantly with other retinotoxic drugs.
Clinically significant interactions are not expected since vigabatrin and.
Atripla and vigabatrin or gabapentin can be coadministered without dose adjustment.
Severe persistent visual field constriction associated with vigabatrin.
Overall summary of the scientific evaluation of vigabatrin containing medicinal products.
Preclinical pharmacokinetic studies in rats provide evidence of melanin binding of vigabatrin.
Vigabatrin should not be used concomitantly with other retinotoxic medicinal products.
No controlled studies are available to assess the efficacy of vigabatrin monotherapy in children.
The pharmacokinetics of vigabatrin in patients with impaired liver function have not been studied.
These events have been reversible following dose reduction or discontinuation of vigabatrin.
Laboratory data indicate that vigabatrin treatment does not lead to renal toxicity.
Activated charcoal has not been shown to significantly adsorb vigabatrin in an in vitro study.
Laboratory data indicate that vigabatrin treatment does not lead to renal or hepatic toxicity.
In patients taking vigabatrin.
Vigabatrin should not be used in patients who already have visual field defects.
Depression was a common psychiatric reaction in clinical trials but seldom required discontinuation of vigabatrin.
Animal experiments have shown that vigabatrin has no negative influence on fertility or pup development.
Details of all cases of visual disorders which have occurred worldwide in patients receiving vigabatrin.
Static perimetry is the preferred method for detecting vigabatrin associated visual field defect.
Available data suggests that visual field defects are irreversible even after discontinuation of vigabatrin.
Such changes have not been seen in vigabatrin treated patients without a VFD.
All patients should have ophthalmological consultation before or shortly after the initiation of vigabatrin treatment.
Vigabatrin and progabide are also analogs of GABA.
No reliable information of the prevalence of VFD attributable to vigabatrin exists in children.
