Examples of 'vinflunine' in a sentence
Meaning of "vinflunine"
Vinflunine (noun): A type of medication used in cancer treatment
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- A particular antitumor drug.
How to use "vinflunine" in a sentence
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vinflunine
Vinflunine did not induce peripheral neuropathy in animals.
There is no known antidote for vinflunine overdose.
Determine the vinflunine content by means of liquid chromatography.
Further studies of the role of vinflunine are warranted.
Alternatively vinflunine may be prepared by direct fluorination of vinorelbine.
The carcinogenic potential of vinflunine has not been studied.
Cases of PRES have been observed after administration of vinflunine.
It is unknown whether vinflunine or its metabolites are excreted in human milk.
There are no data available on the use of vinflunine in pregnant women.
Discontinuation of vinflunine should be considered in patients who develop cardiac ischaemia.
The active substance is vinflunine.
Vinflunine doses were adjusted according to 3 age groups as shown below.
No pharmacokinetic interaction was observed in patients when vinflunine was combined with doxorubicin.
One patient in the vinflunine group died of treatment-related pneumonia.
Either peripheral lines or a central catheter can be used for vinflunine administration.
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Vinflunine should therefore not be used during pregnancy, unless it is strictly necessary.
Other specific structural analogues of vinorelbine and vinflunine are easily accessed by this method.
Few QT interval prolongations have been observed after the administration of vinflunine.
Bronchospam was reported in one patient treated with vinflunine for a different setting from the indication.
Several strategies are being studied for continuing the development of vinflunine 1.
The synthesis of vinflunine could then be accessed vía a biomimetic coupling with vindoline 3.
The pharmacokinetic results of this study indicated a reduction of vinflunine clearance when CrCl is decreased.
Efficacy and safety of vinflunine have not been studied in patients with performance status 2.
Neutropenia, leucopenia, anaemia and thrombocytopenia are frequent adverse reactions of vinflunine.
Vinflunine 1 is a wide-spectrum anticancer agent developed by Pierre Fabre laboratories.
Therefore, regular monitoring of serum sodium levels is recommended during treatment with vinflunine.
When infused through a peripheral vein, vinflunine can induce venous irritation see section 4.4.
Examples of vinca alkaloids and analogs include vinblastine, vincristine, vindesine, vinorelbine, vinflunine.
Vinflunine 1 ( Javlor ® ) is the most active fluorinated compound discovered over recent years.
One mL of concentrate contains 25 mg of vinflunine as ditartrate.
Blood exposure to vinflunine ( AUC ), significantly correlated with severity of leucopenia, neutropenia and fatigue.
Each mL of concentrate contains 25 mg of vinflunine as ditartrate.
Transformation of 30 in vinflunine 1 by ring contraction is described in literature J. - C.
Examples of mitotic inhibitors include paclitaxel, docetaxel, vincristine, vinblastine, vinorelbine, and vinflunine.
A pharmacokinetic phase I study of vinflunine was performed in elderly patients n=46.
The use according to Claim 14 wherein the mitotic inhibitor is vinflunine.
Patients were randomly assigned ( 1:1 ) to receive vinflunine or best supportive care until disease progression.
Package Leaflet, Information for the user Javlor 25 mg / mL concentrate for solution for infusion vinflunine.
It contains the active substance vinflunine 25 mg / l.
In a 100 ml Erlenmeyer, introduce an accurately measured test sample equivalent to 50 mg of vinflunine.
Javlor 25 mg / mL sterile concentrate vinflunine.
Javlor 25 mg / mL concentrate for solution for infusion vinflunine.
