Examples of 'vitronectin' in a sentence
Meaning of "vitronectin"
vitronectin (noun): A glycoprotein that is found in blood plasma and the extracellular matrix of various tissues. It plays a role in cell adhesion and spreading, as well as in the regulation of blood clotting
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- A protein of the pexin family, an abundant glycoprotein that promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors.
How to use "vitronectin" in a sentence
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vitronectin
Pyrimidine derivatives which are antagonists of vitronectin receptor.
Thus vitronectin serves to regulate proteolysis initiated by plasminogen activation.
This is a surprising finding insofar as vitronectin is concerned.
The vitronectin receptor blocker has in vitro inhibited microglial phagoptosis.
One particular example is purified autologous vitronectin.
Osteoclasts are known to express vitronectin receptors which belong to the integrin family.
Pyrimidine derivatives which are antagonist of the vitronectin receptor.
The vitronectin receptor binding compounds target the radioisotope to the tumor neovasculature.
Is an antagonist of protein complexes comprising a growth factor and vitronectin.
It has been shown that uPAR directly binds vitronectin and promotes cell adhesion.
The purified protease cleaves fibronectin and rapidly degrades vitronectin.
It is generally believed that the vitronectin receptor is the major endothelial receptor for fibrinogen.
The lower surface of the filter was coated with vitronectin.
This observation indicates that vitronectin may function as a locally expressed regulator of the protease inhibition.
The lower surface of the filter was coated with vitronectin or osteopontin.
See also
Fibronectin and vitronectin block the uptake of active Tat by MDDC.
Is an antagonist of protein complexes comprising a growth factor and vitronectin or fibronectin.
Inhibition of vitronectin binding by polyclonal antibodies against PE-PilA fusión protein.
Methods for the use of pyrimidine derivatives which are antagonists of vitronectin receptor.
Migration of HUVECS towards vitronectin in the presence of bFGF.
Washing and elution steps were identical to those used in purifying vitronectin receptor.
Migration of HUVECS towards vitronectin in the presence ofbFGF.
The color developed is directly proportional to the amount of antibody fixed to the vitronectin.
The cells were then placed on vitronectin plates, washed and stained.
All synthesized peptides were tested for their ability to inhibit cell adhesion to vitronectin.
Preferred compounds inhibit vitronectin binding at a concentration of less than 1 micromolar.
This invention is also a method of treating diseases which are mediated by the vitronectin receptor.
For example, the vitronectin receptor on osteoclasts is known to inhibits osteoclastic bone resorption.
Western blotting is then performed to identify specifically bound components such as fibronectin and vitronectin.
At least an integrin-binding domain of vitronectin or fibronectin.
Fibronection, vitronectin and thrombospondine are examples of the proteins which bond to GPIIb / IIIa.
RGD is found in all of the ligands identified above for the vitronectin receptor integrins.
Fibronectin, vitronectin and thrombospondin are proteins which have also been demonstrated to bind to GPIIb-IIIa.
These serum factors are not the adhesion factors Fibronectin or Vitronectin.
However, the mechanism by which plasma vitronectin associates with the extracellular matrix remains unclear.
Aureus expresses surface receptors for fibrinogen, fibronectin, and vitronectin.
Podocytes are able to produce vitronectin as tested by RT-PCR.
Schematic depiction of uPAR in complex with avB3 integrin and vitronectin.
In humans, vitronectin is encoded by the VTN gene.
Examples of suitable thrombogenic agents include collagen, fibrinogen, and vitronectin.
It will also be appreciated that vitronectin ( VN ) may be in monomeric or multimeric form.
Is an agonist of protein complexes comprising a growth factor and vitronectin or fibronectin ; or.
Inhibition of vitronectin binding to PE by polyclonal antibodies directed against PE-PilA was observed.
These cell surface adhesion receptors include the vitronectin receptor avB3.
Wherein Q is a vitronectin receptor antagonist, a somatostatin analog, or a growth factor receptor antagonist.
Control wells are coated with a known adhesive protein, such as fibronectin or vitronectin.
RGD-containing peptides that inhibit vitronectin receptor avB3 have also been described.
The compounds are very particularly active as adhesion receptor antagonists for the vitronectin receptor avB3.
In addition, vitronectin is a component of platelets and is, thus, involved in hemostasis.
Studies were conducted to define the binding site ( s ) for vitronectin in fibroblast cell layers.
