Examples of 'vortioxetine' in a sentence
Meaning of "vortioxetine"
Vortioxetine is an adjective that refers to a specific medication used to treat depression
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- A particular atypical antidepressant.
How to use "vortioxetine" in a sentence
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vortioxetine
The major metabolite of vortioxetine is pharmacologically inactive.
Brintellix contains the active substance vortioxetine.
The efficacy of vortioxetine increased with increasing dose.
There is limited experience with vortioxetine overdose.
Potential for vortioxetine to affect other medicinal products.
In toluene together with a palladium catalyst to afford vortioxetine.
The molecular structure of vortioxetine is depicted below.
Vortioxetine was administered subcutaneously and donepezil was administered intraperitonealt.
The molecular structure of vortioxetine free base is depicted below.
Vortioxetine was administered as the HBr salt.
The active substance is vortioxetine.
The amounts of vortioxetine pyroglutamate are indicated as free base.
Brintellix is an antidepressant medicine containing the active substance vortioxetine.
Vortioxetine is initially brought into solution as the pyroglutamate salt.
There are limited data from the use of vortioxetine in pregnant women.
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The place of vortioxetine in the treatment of acute depression is unclear.
By photolysis to obtain vortioxetine.
Vortioxetine did not increase the incidence of insomnia or somnolence relative to placebo.
A pharmaceutical composition comprising vortioxetine and donepezil together with a pharmaceutically acceptable excipient.
Vortioxetine was not genotoxic in a standard battery of in vitro and in vivo tests.
The use of aqueous HBr may achieve the HBr salt of vortioxetine in one step.
Vortioxetine is considered a safe medicine for long term use in most people.
The compound of formula I may then be further reacted as described above to obtain vortioxetine.
You may feel that vortioxetine is not working for you straightaway.
Detailed Description of the Invention The present invention relates to pyroglutamate salts of vortioxetine.
Vortioxetine has in clinical trials shown to be a safe and efficacious treatment for depression.
In comparison to SNRIs, we found no advantage for vortioxetine.
The combined administration of vortioxetine and donepezil may take the form of simultaneous administration.
Accordingly, in one embodiment, the invention relates to vortioxetine pyroglutamate.
Vortioxetine HBr in an IR formulation is now approved in many major markets.
In this embodiment, either vortioxetine or donepezil may be administered first.
Vortioxetine had a statistically significant effect versus placebo on the Digit Symbol Substitution Test.
In the dedicated study in elderly, vortioxetine was also effective in these patients.
In one embodiment, the invention relates to a pharmaceutical composition comprising vortioxetine pyroglutamate.
Each film-coated tablet contains vortioxetine hydrobromide equivalent to 5 mg vortioxetine.
In one embodiment, the invention provides an enteric coated formulation comprising vortioxetine pyroglutamate.
Vortioxetine is a poor P-gp substrate and inhibitor.
Available data in animals have shown excretion of vortioxetine / vortioxetine metabolites in milk.
Vortioxetine is present on the market as the hydrobromide salt, under the tradename Brintellix ®.
In one embodiment, the invention relates to vortioxetine pyroglutamate for use in therapy.
Vortioxetine - Angioedema and urticaria EPITT no.
That is, a synergistic effect on acetylcholine levels between vortioxetine and donepezil has been demonstrated.
It is expected that vortioxetine will be excreted into human milk see section 5.3.
Accordingly, in one embodiment, the present invention relates to a composition comprising vortioxetine and donepezil.
The newer and widely used antidepressant vortioxetine ( Trintrellix ) was not analysed by the Belgian doctors.
Injection of galantamine was 60 minutes prior to the injection of vortioxetine.
There is limited experience with vortioxetine overdoses above 80 mg.
Package leaflet, Information for the patient Brintellix 10 mg film-coated tablets vortioxetine.
The pharmacological profile gives reason to believe that vortioxetine may have a pro-cognitive effect.
The spectrum shows that vortioxetine ( DL ) pyroglutamate a-form is essentially in a crystalline form.
