Examples of 'wild-type protein' in a sentence
Meaning of "wild-type protein"
wild-type protein: This phrase refers to a protein that is the typical form found in nature, without any mutations or variations. It is commonly used in genetics and biology to distinguish between naturally occurring proteins and those that have been altered through genetic modifications
How to use "wild-type protein" in a sentence
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wild-type protein
Through the immunoblot of wild-type protein on mutant proteinFIG.
It also encompasses proteins having significant sequence identity to the wild-type protein.
The protein variant may be a wild-type protein that differs to a related protein.
In one aspect, a framework polypeptide is derived from a wild-type protein molecule.
In a further aspect, the wild-type protein is a therapeutic protein.
The first letter designates the amino acid in the wild-type protein.
Wild-type protein expression, however, is inhibited within the cell line.
These proteins were prepared in the same manner as for the wild-type protein.
A variant comprising a deletion relative to wild-type protein may be referred to as a " fragment . ".
Deletion variants lack one or more residues of the native, unaltered or wild-type protein.
The patients are then administered enough of the wild-type protein to elicit an immunological response.
This domain plays an extremely important role in modulating the activity of the wild-type protein.
The ActRIIB-Fc mutant or wild-type protein was loaded onto the system, and binding was measured.
The two mutants were again found to be more stable than the wild-type protein.
The ActRIIB-Fc variants or wild-type protein were captured onto the system using an anti-hFc antibody.
See also
Typically, active fragments are fragments that retain substantially the same activity as the wild-type protein.
The wild-type protein used for stability measurements is described under Example 19.
Thus, a protein produced by readthrough activation may possess activity strongly similar to the wild-type protein.
The sequence presented in FIG . 1 corresponds to the wild-type protein found in European populations.
Additionally, the modified polypeptide has also exhibited improved solubility than the wild-type protein.
In some embodiments, the Tn5 wild-type protein or its variant can further comprise a fusión polypeptide.
The AS protein conserves the transcription-activating capacity of the wild-type protein.
Clone the wild-type protein cDNA ( alternatively, purchase the cDNA ).
An Env+ transductant selected from this strain had the wild-type protein pattern restored.
The typical wild-type protein comprises 152 amino acids and, optionally, an additional N-terminal methionine residue.
A preferred inactive Yes protein will have diminished kinase activity as compared with the wild-type protein.
Wild-type protein is expressed in E. coli ., while the muteins are expressed in yeast ( Pichia pastoris ).
In one embodiment, the target protein is a wild-type protein.
Values reflect X-fold enhanced activity over the wild-type protein ( X = the ratio reported in the Table 1 ).
A plasma-derived protein may also be a naturally-occurring protein and a wild-type protein.
The method of claim 1, wherein the RecA protein is the wild-type protein of Escherichia coli.
Even more preferred are muteins having at least 90 % overall sequence homology to the wild-type protein.
In some embodiments, the H-NOX protein is a wild-type protein.
Generally speaking, a mutein possesses some modified property, structural or functional, of the wild-type protein.
This mutant therefore encodes a truncated protein comprising the first 452 amino acids of the wild-type protein.
In some embodiments of the uses, the H-NOX protein is a wild-type protein.
In some embodiments of the methods, the H-NOX protein is a wild-type protein.
In some embodiments of the compositions, the H-NOX protein is a wild-type protein.
As a control FabD10SCP was incubated with a-glucosidase wild-type protein.
Mutations, which transcriptional activity has decreased to 50 % of that of the wild-type protein.
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These may be wild-type or derivative sequences
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Wild-type enzyme controls are shown as well
