Examples of 'wnt pathway' in a sentence
Meaning of "wnt pathway"
Wnt pathway - A signaling pathway involved in cell-to-cell communication during development and adult tissue homeostasis. It plays a crucial role in cell proliferation, cell polarity, and cell fate determination
How to use "wnt pathway" in a sentence
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wnt pathway
Wnt pathway mediates synaptic structural changes induced by neuronal activity or experience.
Recent studies show that there is an association between wnt pathway and aurora kinase proteins.
Upregulation of the Wnt pathway influences that differentiation as is disclosed in the examples.
Tankyrases have reportedly been implicated in the regulation of Wnt pathway.
Inappropriate activation of the Wnt pathway has been reported in many cancers.
Some embodiments involving detection further comprise detection of Wnt pathway activation.
Aberrant activation of the Wnt pathway can lead to increase cell proliferation.
Inhibition or reduction of this activity is useful for reduction of Wnt pathway activity.
There is no strong dependence of the Wnt pathway for enteroendocrine cell differentiation.
This molecular approach is enhanced by the combination with a pharmacological stimulation targeting the Wnt pathway.
Aberrant regulation of the Wnt pathway has been associated with many cancers.
Currently, there is a dearth of research on the WnT pathway.
Body of evidences point out the Wnt pathway role in the maintenance of BBB integrity.
For example, the LiCl is used in the medium because it stimulates the wnt pathway.
Future research will explore why the Wnt pathway seems particularly important in the healing process.
See also
In certain aspects, the therapeutic agent is a wnt pathway antagonist.
The Wnt pathway is a target for anti-cancer therapy.
The composition includes a pharmaceutically acceptable carrier and a Wnt pathway inhibitor as described herein.
For example, the Wnt pathway comprises a cascade of proteomic reactions.
In some aspects, the agent is a wnt pathway antagonist.
Thus, Wnt pathway involvement in the etiology of thyroid ectopy is biologically plausible.
The ability of the FZD antibodies to inhibit Wnt pathway activation is thus determined.
However, it could also be preferred to activate or overexpress a component of the Wnt pathway.
It also is a direct target gene of the Wnt pathway and is upregulated by beta-catenin.
The asymmetric division in these cells is regulated by cancer niche ( microenvironment ) and Wnt pathway.
Aberrant over-activation of Wnt pathway can be involved in causing tumorigenesis of colorectal carcinomas.
In certain aspects, the candidate agent is a wnt pathway antagonist.
Activation of the Wnt pathway promotes differentiation into osteoblasts, but also prevents fat cell formation.
Wnt3a is a soluble compound that up regulates the Wnt pathway in cells.
The classic canonical Wnt pathway involves B-catenin protein as a signaling mediator.
Culturing the mammalian somatic cell in a culture medium containing the Wnt pathway activator ; or.
Activation of the Wnt pathway by Wnt3a enhances reprogramming mediated by cell fusion.
After damage by CC14 cells also cells not lining duct have an activated Wnt pathway.
Mutations have also been identified in other Wnt pathway components including auxin and B-catenin.
Wnt pathway activation results in Dishevelled-induced inactivation of the B-catenin phosphorylation complex.
Without a working APC brake, the Wnt pathway is stuck in the “ on ” position.
Wnt pathway members levels can be determined by flow cytometry, FRET, immunoblotting, or other means.
Example 9 . rSIFN-co induced transcriptional down-regulation of Wnt pathway mediated target genes.
Nanog over-expression and Wnt pathway activation cooperate to enhance reprogramming of NS cells.
For example, over 90 % of colorectal cancers bear mutations that result in Wnt pathway activation.
However, the Wnt pathway is present ( albeit possibly inactive ) in all cells.
Thus, a correlation between the " CTNNB 1 " group and high Wnt pathway activity is conform expectation.
However, the Wnt pathway is present ( albeit possibly inactive ) in other cell types.
Alternatively, LRP6 can be immobilized, and Wnt pathway member binding thereto can be detected.
The method of any one of claims 1-3, wherein the cellular signaling pathway comprises a Wnt pathway.
In healthy adult pancreas, the Wnt pathway is inactive and - consequently - Lgr5 is not expressed.
This analysis produced a gene signature for Wnt pathway activity ( Table 6 ).
Usag-1 ( Wise ) may be functioning through the Wnt pathway for its role in renal protection.
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