Examples of 'zinc fingers' in a sentence
Meaning of "zinc fingers"
zinc fingers - specialized protein motifs that can bind to specific DNA sequences and are important for gene regulation
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- plural of zinc finger
How to use "zinc fingers" in a sentence
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zinc fingers
Zinc fingers can also be selected by design.
Polynucleotides encoding zinc fingers or zinc finger proteins are also disclosed.
Zinc fingers can be manipulated to recognize a broad range of sequences.
A zinc finger binding domain comprises one or more zinc fingers.
Some zinc fingers can bind to a fourth base in a target segment.
Their secondary and tertiary structure is distinct from that of classic zinc fingers.
There is no information whether the zinc fingers are involved in DNA binding.
NC is a nucleic acid chaperone protein with two zinc fingers.
Specific DNA binding zinc fingers can be selected by using polypeptide display libraries.
Subject matter of the invention are only those zinc fingers defined in the claims.
In general, zinc fingers coordinate zinc ions with a combination of cysteine and histidine residues.
The homology searching function of RecA can substitute for the zinc fingers in this system.
Conferred through three zinc fingers in the DNA-binding domain.
Zinc finger binding domains A zinc finger binding domain comprises one or more zinc fingers.
Afterwards, the recombined zinc fingers are screened vía a bacterial two-hybrid system.
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Alternatively, modules can be constructed by assembly of individual zinc fingers.
In addition, zinc fingers have become extremely useful in various therapeutic and research capacities.
Various strategies have been developed to engineer Cys2His2 zinc fingers to bind desired sequences.
Proteins that contain zinc fingers ( zinc finger proteins ) are classified into several different structural families.
Thus, new specificities are created by rearranging the order of zinc fingers in multi-finger proteins.
In this way, different numbers of zinc fingers could be tested for optimal length-dependent discrimination.
Lower-case letters represent nucleotides not directly contacted by the constituent zinc fingers of the protein.
However, zinc fingers have not been shown to interact with RNA.
The best-characterized proteins containing treble-clef zinc fingers are the nuclear hormone receptors.
Two GATA zinc fingers are found in GATA-family transcription factors.
In particular, described herein are CCHC zinc fingers.
Mutation of the Zinc fingers or inactivation of WT1 results in reduced male gonad size.
The isolated zinc finger DNA binding protein of claim 1, consisting of three zinc fingers.
Thus, several zinc fingers can be combined in order to bind a desired DNA element.
Next, chimeric nucleases were designed each comprising 3 zinc fingers.
These zinc fingers can be found in several transcription factors including the yeast Gal4 protein.
The zinc is normally held in NC proteins by 1 or 2 zinc fingers.
The non-canonical zinc fingers disclosed herein retain this beta-beta-alpha structure.
In the case of a ZFN, the DNA-binding domain comprises one or more zinc fingers.
Three zinc fingers are positioned in a semi-circular or C-shaped arrangement.
The transcription factor SP1 contains three Krüppel-like zinc fingers.
These zinc fingers are of the NZF type, and are the ubiquitin-binding motifs.
GATA proteins have two highly conserved domains, the N-terminal and the C-terminal zinc fingers.
ZEB1 protein has 7 zinc fingers and 1 homeodomain.
Zinc fingers are randomized, e.g., by using degenerate oligonucleotides, mutagenic cassettes, or error prone PCR.
The predicted protein contains 9 typical C2H2 zinc fingers in its C-terminal region.
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Examples of using Fingers
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I want to run my fingers through your hair
Examples of using Zinc
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Zinc is not very mobile within plants
Do not inhale zinc phosphide dust or fumes
Zinc and copper will be included as before
