Examples of 'zymogen' in a sentence
Meaning of "zymogen"
zymogen, a noun denoting an inactive enzyme precursor that requires a biochemical change to become an active enzyme, commonly found in biological organisms as a way to regulate enzymatic activity
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- A proenzyme, or enzyme precursor, which requires a biochemical change (i.e. hydrolysis) to become an active form of the enzyme.
How to use "zymogen" in a sentence
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zymogen
The zymogen has marginal catalytic activity.
Mesotrypsin is expressed in both constructs as an inactive zymogen.
The zymogen is activated by removing the propeptide domain.
This inactive form is called a zymogen.
A zymogen is an inactive precursor of a proteolytic enzyme.
Asparagine endopeptidase is synthesized as an inactive zymogen.
Zymogen cells play a significant role in the course of regeneration.
The mesotrypsin catalytic domain was expressed as an inactive zymogen.
During regeneration zymogen cells played a very important role.
It is disclosed that the coagulation factor is an inactive zymogen.
The zymogen is catalytically inactive.
The biochemical term for such proenzymes is zymogen.
Trypsin is produced as the inactive zymogen trypsinogen in the pancreas.
The metacaspases as caspases are expressed in the form of inactive zymogen.
Other examples include papain zymogen and papain active protein.
See also
The inactive conformation is similar to that of the corresponding zymogen.
The zymogen mutants may be purified from the cell cultures.
This type of inactive precursor to an enzyme is known as a zymogen or proenzyme.
Protein c zymogen and methods of use thereof to prevent cancer metastases.
Thrombin is produced by the enzymatic cleavage of the zymogen prothrombin.
Zymogen to protease conversion.
The sensitivity of the zymogen.
The zymogen includes a signal enzyme that is inhibited by the peptide substrate.
The enzyme is secreted as zymogen.
Proinsulin us the zymogen which is cleaved to form the active hormone insulin.
The type of assay with which the zymogen will be used.
Also described herein is a sensor for the detection of a microorganism comprising a synthetic zymogen.
Plasmin can also catalyze activation of the zymogen forms of several metalloproteinases.
The drug precursors of the present invention are in certain cases a proenzyme or a zymogen.
The difference in activity between the zymogen and the signal enzyme.
The zymogen contains one or more epitopes not associated with the truncated enzyme.
Blood coagulation may occur through either of two cascades of zymogen activations.
Upon cleavage of this sequence the zymogen is converted to its enzymatically active state.
With the extra peptide sequence the enzyme is in the inactive zymogen state.
Frequently the zymogen has an amino terminal sequence that blocks the catalytic site.
These fibrinolytic agents convert the inactive zymogen plasminogen into plasmin.
Substrate binding and interaction with inhibitor both require extracellular activation of the collagenase zymogen.
Factor XII is an inactive zymogen present in normal blood.
The application also describes sensor for the detection of a microorganism comprising a synthetic zymogen complex.
It is found in plasma as an inactive zymogen that is activated by Factor XIIa.
All MMPs are synthesized in the latent form Zymogen.
Zymogen factor XIII is activated by thrombin present on the fibrin surface.
Plasminogen activators universally exert their thrombolytic potential by activating circulating zymogen plasminogen into plasmin.
MMPs are secreted in an inactive zymogen form following cleavage of a signal peptide.
MMPs are secreted in the extracellular matrix in their zymogen form.
Plasma factor XIII zymogen is a tetramer consisting of two a subunits and two b subunits.
Active FXIa is produced from FXI by proteolytic cleavage of the zymogen by FXIIa.
PKA is both an activator of the zymogen form of urokinase and a direct plasminogen activator.
Protein C in its inactive form as a zymogen is usable.
Factor X is a zymogen and has no enzymatic activity.
