Examples of 'aβ' in a sentence
Meaning of "aβ"
aβ (noun) - typically refers to beta-amyloid (Aβ), a protein associated with Alzheimer's disease. It forms plaques in the brain and is linked to neurodegeneration
How to use "aβ" in a sentence
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aβ
Aβ uses several routes in the central nervous system to cause cell death.
The normal function of Aβ is not well understood.
Aβ was also found aiding this route to neurotoxicity by enhancing neuron vulnerability to glutamate.
A portion of this protein contains an Aβ peptide sequence.
Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms.
This result confirmed studies on the Aβ precursor.
Prevention of oligomerization of Aβ has been exemplified by active or passive Aβ immunization.
Aβ is a fragment from the larger amyloid precursor protein APP.
It is generally believed that Aβ oligomers are the most toxic.
Early detection of the presence of Aβ.
Ashwagandha can also help reduce Aβ deposits in the brain.
Soluble oligomers and protofibrils are the most toxic species of Aβ.
Together they would decrease the total Aβ deposition in brain.
It commences with Aβ deposits developing in the brain of AD cases.
These findings suggest that IDE activity is capable of joining of several Aβ fragments together.
See also
Recent findings shows that Aβ aggregates transmit Aβ pathology to experimental animals.
This phenotypic rescue was accompanied with the decrease of both Aβ levels and amyloid plaques.
Second, plasma Aβ could mediate peripheral insulin resistance.
Transmission electron microscopy revealed retinal Aβ assembled into protofibrils and fibrils.
The pathology of AD is also associated with accumulation of amyloid beta peptide Aβ.
Several reports have documented the inhibition of Aβ plaque formation by compounds from natural sources.
AD may also impair LTP through mechanisms distinct from Aβ.
Then we investigated whether Aβ peptides could be one of the neprilysins ' targets.
Reduction of Aβ.
Since the brain Aβ deposits accumulate over time, the effect is integral.
However, it did not affect the formation of Aβ.
However, the significance of the lymphatic system in Aβ clearance in Alzheimer 's disease is unknown.
A buildup of Aβ within cells causes inflammation, leading to cell destruction by the immune system.
There is also experimental evidence for cross-seeding between prion protein and Aβ.
The steady-state level of Aβ depends on the balance between production and clearance.
Approximately 60 hits showed clear evidence of consensus and specific recognition of the pathogenic Aβ substrate.
These Aβ aggregates then grow into significantly larger senile plaques, a pathological marker of Alzheimer 's disease.
The antibody aducanumab reduces Aβ plaques in Alzheimer 's disease.
Aβ is produced by the proteolysis of a transmembrane protein named Amyloid Precursor Protein ( APP ).
This mutation, the so-called Swedish mutation, was known to result in an overproduction of Aβ.
TUDCA reduced Aβ plaques in the brains of mice with symptoms of Alzheimer 's disease.
Isolation of cDNA encoding proteins associated with Aβ was used to discover alpha-2-macroglobulin.
Aβ is a proteolytic degradation product of a larger molecule called amyloid-β protein precursor ( AβPP ).
This raises questions about the central role of Aβ peptides in Alzheimer 's disease pathology . ”.
In vitro, Aβ causes L-glutamate discharge from primary microglia through the upregulation of program x-c.
The machine contains p+2 deterministic finite automaton and a master controller, where p is the size of Aβ.
Non-nociceptive neurons ( or Aβ fibers ) are the ones that send the touch signal.
Aβ forms soluble aggregate (Aβ oligomer) and insoluble aggregate (Aβ fibril).
Interestingly, pre-incubation of Wnt5a prevents toxicity of Aβ oligomers and maintains basal AMPARs dynamics.
However, Aβ generation was also shown to be increased in AMPK deficient mice ( R ).
As previously, the protonation of a histidine residue present on Aβ wasobserved at pH < 6,5.
During Alzheimer 's disease, Aβ peptides aggregate to form toxic plaques.
The rest of p+1 machines are copies of Aβ.
Paper: “The antibody aducanumab reduces Aβ plaques in Alzheimer's disease”.
In mice brain, sNEP-scFv8D3 was detected in same areas as Aβ aggregates.
