Examples of 'affinity ligands' in a sentence
Meaning of "affinity ligands"
affinity ligands: Affinity ligands are molecules or compounds that exhibit a high affinity or binding capacity for a specific target, such as proteins, enzymes, or receptors. They are frequently used in biochemical and biotechnological applications to capture, purify, or detect biomolecules of interest based on their selective binding interactions
How to use "affinity ligands" in a sentence
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affinity ligands
Oligopeptides are capable of serving as affinity ligands as well.
In this case affinity ligands could be synthesised as soluble particles.
Of particular interest as large molecule affinity ligands are lectins.
The corresponding affinity ligands are also well known in the art.
Short peptides are capable of replacing antibodies as affinity ligands.
Such affinity ligands and methods for obtaining them are provided herein.
Also suitable for use as large molecule affinity ligands are polynucleic acid aptamers.
Isolation of affinity ligands in accordance with this invention will be further illustrated below.
The recombinantly produced proteins of the invention are particularly useful affinity ligands for chromatographic purification.
The affinity ligands usually are mimetic dyes and sometimes also monoclonal antibodies.
SELEX provides high affinity ligands of a target molecule.
Field of the Invention This invention relates to compounds and their use as affinity ligands.
Examples of suitable affinity ligands are available in the published literature and are well known.
In a specific embodiment, the metal chelating affinity ligands are tridentate.
Preferred affinity ligands according to the invention are,.
See also
These antibodies therefore constitute the precursors of affinity ligands of macrophages,.
In this case, affinity ligands could be synthesized as soluble particles.
Murine monoclonal antibodies ( MAbs ) have been used effectively as affinity ligands.
SELEX delivers high affinity ligands of a target molecule.
In addition to non-immunoglobulin proteins, oligonucleotides may also be used as affinity ligands.
The SELEX process provides high affinity ligands of a target molecule.
The interactive moieties can be, for example, chemical groups of affinity ligands.
In addition, other high affinity ligands may be used.
In a method of the invention, a solid phase material is used that carries affinity ligands.
In addition, other high affinity ligands including cathepsin derivatives may be used.
In certain embodiments, the tag section comprises affinity ligands such as biotin.
Therefore, the use of affinity ligands produced by organic-chemical synthesis would be advantageous.
Non-covalent binding includes binding vÃa biotin affinity ligands binding to steptavidin matrices.
The affinity ligands can be associated with the capture-particle in any suitable way.
In a further aspect of the invention, the solid phase material carries affinity ligands.
This indicates suitable affinity ligands with a relatively clean release upon lowering the pH to 5.
The process according to claim 9, wherein said biochemical technique comprises use of biochemical affinity ligands.
Moreover, high affinity ligands can not be measured, due to the applied relaxation filter.
Therefore, the SELEX process can be used to provide high affinity ligands of a target molecule.
High affinity ligands from family 1 and family 2 may bind to different sites on bFGF.
Murine monoclonal antibodies ( MAbs ) also have been used as affinity ligands.
Both are high affinity ligands for AR, with dihydrotestosterone having somewhat higher affinity.
FE, in this case, may be any of a number of high affinity ligands.
Suitable affinity ligands include the FGFR2IIIb ECD and ligands that bind antibody constant regions.
Thus, Rspo3 can be added to the list of high affinity ligands of syndecans.
Subsequently, affinity ligands for PDE4D7 may be applied, preferably antibodies or aptamers.
A sub-fraction of SEA contains high affinity ligands for DC-SIGN.
Affinity ligands according to claim 34 wherein m is 1.
Each sample was then loaded onto the RIKSI M test kit, which contained 10 different affinity ligands.
Roughly 50 % of the high affinity ligands tested were inhibitors.
Affinity ligands according to anyone of claims 28 to 51 selected among the following,.
Affinity ligands according to claim 34 wherein I is an ethyl, butyl, or hexyl group.
Affinity ligands according to claim 34 wherein V represents a - NH - group.
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Examples of using Ligands
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Imido ligands can be terminal or bridging ligands
Bipyridine and related ligands behave similarly
Such ligands are useful in the hydroformylation of alkenes
