Examples of 'affinity matured' in a sentence
Meaning of "affinity matured"
Affinity matured: In the context of biology, this phrase refers to the process by which an antibody binds more tightly to an antigen over time, resulting in a stronger immune response
How to use "affinity matured" in a sentence
Basic
Advanced
affinity matured
The invention includes affinity matured embodiments.
Affinity matured embodiments can also be used.
The antigen binding site may be affinity matured.
Affinity matured antibodies are produced by known procedures.
Various forms of the humanized or affinity matured antibody are contemplated.
Affinity matured antibodies are produced by procedures known in the art.
In addition it has the advantage to result in affinity matured antibodies.
Affinity matured antibodies are therefore also embraced in the present invention.
This term also encompasses affinity matured forms of such antibodies.
Affinity matured antibodies can be produced by procedures known in the art.
The antibodies resulting from the library screen are affinity matured.
Affinity matured antibodies may be produced using certain procedures known in the art.
Selected monoclonal antibodies were then humanized and affinity matured for further characterization.
The affinity matured antibodies may also be characterized using the assays described herein.
The present disclosure demonstrates the purposeful isolation of affinity matured antibodies vÃa cell surface display.
See also
Affinity matured antibodies may have nanomolar or even picomolar affinities to the receptor antigen.
In some embodiments, the antibody is affinity matured.
Affinity matured modular antibodies may exhibit a several logfold greater affinity than a parent antibody.
In one embodiment, the antibody is affinity matured.
Preferred affinity matured antibodies will have nanomolar or even picomolar affinities for the target antigen.
In some embodiments, the antibody is an affinity matured antibody.
The affinity matured families of each of these is presented below in Tables IV and V.
In still other embodiments, the antibody is affinity matured.
All 8 affinity matured antibodies do not bind prekallikrein.
In still other embodiments, the antibody of the invention is affinity matured.
Parental and affinity matured anti-TFPI antibodies were in the mobile phase.
The antibody of claim 2, wherein the antibody is an affinity matured form of the antibody.
Preferred affinity matured antibodies will have very high affinities, e . g.
The sites selected for modification may be affinity matured using phage display ( see above ).
An affinity matured form of the antibody of ( a ) ;.
For example, the humanized antibody or affinity matured antibody may be an antibody fragment.
An antibody can be human, humanized and / or affinity matured.
Selection of an affinity matured version of the humanized 6G4.
Figure 17 depicts the sequences of three affinity matured candidates.
Example 5 - The use of affinity matured anti-ED-B scFvs in in vivo targeting of human tumours.
A full length antibody can be human, humanized and / or affinity matured.
Dose-response analysis of the efficacy of affinity matured mAb in huGM-CSFR Tg chimeric mice.
Characterization of the affinity matured variant anti-CD19 Fabs isolated from the combinatorial phage display library.
Example 5 - Generation and purification of affinity matured antigen binding sites.
The following affinity matured TN8-19 family of peptides are shown in Table IV below.
The present application also contemplates affinity matured antibodies which bind HER2.
The section also describes the in vitro characterization of the affinity matured anti-CD 19 antibodies.
Example 3 - Specificity of affinity matured scFvs for ED-B-containing fibronectins.
Table VIII shows IC50 values for a number of affinity matured peptibodies.
Cell surface staining by affinity matured anti-CD19 antibodies.
The IgM-positive hybridomas were affinity matured ( Figure 6 ).
Coomassie stained IEF-PAGE of affinity matured anti-CD19 antibodies.
PK15 derives from library 2 and is an affinity matured inhibitor.
You'll also be interested in:
Examples of using Affinity
Show more
Expose his unholy affinity for savages
My affinity with the radio operator was confirmed
We have a basic affinity for our family
Examples of using Matured
Show more
They need to be matured for a long time
I matured three and a half years ago
I have grown and matured since then
