Examples of 'allosteric modulator' in a sentence
Meaning of "allosteric modulator"
An allosteric modulator is a substance or compound that can bind to a specific site on a protein or enzyme and affect its activity. It is often used in the context of pharmacology and biochemistry to describe the mechanisms through which certain drugs or compounds can regulate protein function
How to use "allosteric modulator" in a sentence
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allosteric modulator
Homotropic allosteric modulator.
Allosteric modulator of GABAA receptors.
Heterotropic allosteric modulator.
However, it is much more difficult to develop a clinically relevant positive allosteric modulator.
Positive allosteric modulator.
At low or moderate doses, alcohol acts primarily as a positive allosteric modulator of GABAA.
Zinc is a negative allosteric modulator of the GABAA receptor.
In certain embodiments a compound of the invention acts as a positive allosteric modulator of GLP-1 receptor.
CBD is an allosteric modulator at several receptor sites in our bodies.
It is also possible to use a ligand that is an allosteric modulator of these receptors.
It is a positive allosteric modulator at the benzodiazepine binding site of GABAA receptors.
It acts as a GABAergic agent and as a positive allosteric modulator of GABAA receptor.
It acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.
Allopregnanolone acts as a highly potent positive allosteric modulator of the GABAA receptor.
A receptor allosteric modulator comprising a cyclic polypeptide according to claim 1.
See also
It has also been found to act as a negative allosteric modulator of the GABAA-rho receptor.
A heterotropic allosteric modulator is a regulatory molecule that is not the enzyme 's substrate.
List of investigational sleep drugs GABAA receptor negative allosteric modulator GABAA receptor § Ligands.
It is a positive allosteric modulator of the GABAA receptor, similarly to isovaleric acid.
The pharmaceutical composition according to claim 13, which is a GABAB positive allosteric modulator.
Chromone oxime derivative and its use as allosteric modulator of metabotropic glutamate receptors.
Positive allosteric modulator pEC50 values and antagonist pIC50 values for each compound were then determined.
AMPA receptor positive allosteric modulator AdisInsight.
The pharmaceutical composition according to claim 12, which is a dopamine D1 receptor positive allosteric modulator.
It is an optimistic allosteric modulator of AMPA receptor.
In one embodiment, the a7-nAChR activator used is an a7-nAChR positive allosteric modulator.
Cannabidiol is a negative allosteric modulator of the type 1 cannabinoid receptor.
Compounds with allosteric modulator activity, such as Example 18, evoke concentration-dependent increases in ERK phosphorylation.
Methylphenylpiracetam is a positive allosteric modulator of the sigma-1 receptor.
It is an allosteric modulator of the μ - and δ-opioid receptors as well.
Some of the natural nootropics act as a positive allosteric modulator for acetylcholine or glutamate receptor [ 9 ].
Is a selective allosteric modulator of the a7 nicotinic-receptor ; and / or.
Hydrochlorothiazide ( HCTZ ) AMPA receptor positive allosteric modulator Glucose-elevating agent.
The “ positive allosteric modulator ( PAM ) ” means a compound having the PAM action.
More specifically, CBD works [ 2 ] as a positive allosteric modulator of the GABA-A receptor.
Clomethiazole acts as a positive allosteric modulator at the barbiturate / picrotoxin site of the GABAA receptor.
More specifically, the positive allosteric modulator binds the receptor at an allosteric site.
Alcohol also acts as a positive allosteric modulator of GABA receptors, specifically type GABAA.
Another antagonist or allosteric modulator of the cannabinoid CB 1 receptors ;.
Cannabidiol ( CBD ) also acts as an allosteric modulator of the μ - and δ-opioid receptors.
A GABA A a5 negative allosteric modulator selected from,.
In one embodiment, the a7-nAChR positive allosteric modulator has a maximum molecular weight of 500 daltons.
No, Diazepam is an allosteric modulator for anxiety . - Same thing, right?
An As adenosine receptor allosteric modulator AsRM, having the following general formula ( I ), wherein,.
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Examples of using Allosteric
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Possible allosteric effects in extended biological systems
This molekule should to act as allosteric activator
Direct and allosteric control of glutamate receptors
Examples of using Modulator
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Mount the modulator cover and seal
Or some nut job with a voice modulator
We added a polaric modulator to the coaxial drive
