Examples of 'amine protecting group' in a sentence
Meaning of "amine protecting group"
Amine protecting group: In organic chemistry, an amine protecting group is a functional group temporarily added to an amine compound to prevent undesired reactions during chemical transformations. It masks the reactive amine functionality, allowing selective modifications elsewhere in the molecule
How to use "amine protecting group" in a sentence
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amine protecting group
Pr represents an amine protecting group or a hydrogen.
Pg, at each occurrence, is independently selected from an amine protecting group.
The most preferred amine protecting group is allyloxycarbonyl.
Solvent selection is based on the identity of the imidazolidine derivative-forming amine protecting group reagent.
Any other suitable amine protecting group may be used.
Any amine protecting group suitable for peptide synthesis is suitable.
Rr is hydrogen or an amine protecting group.
Any amine protecting group known in the art can be used.
A preferred acid labile amine protecting group is BOC.
Suitably the amine protecting group is one which is inert to reduction by a metal hydride.
A preferred hydrogenation labile amine protecting group is Cbz.
Reaction with an amine protecting group reagent forms a protected dinitrile.
The final step is cleagage of the amine protecting group PG.
P is an amine protecting group.
In another specific embodiment of the second aspect, P3 is an amine protecting group.
See also
Removal of the cyclic amine protecting group gives the desired product.
Examples of suitable protective groups ( PG ) include hydrogen or a suitable amine protecting group.
Any suitable amine protecting group can be used in the method described above.
Hydrolysis of the ester and removal of the amine protecting group affords amino acids 23.
Removal of the amine protecting group Pb is accomplished by techniques known in the art.
At this point, the secondary amine is protected with an amine protecting group P4.
The instability of the amine protecting group ( trifluoroacetyl group ) was likewise investigated.
It is preferred that R1 is an amine protecting group.
For example, an amine protecting group such as arylmethyl may be removed by hydrogenolysis.
As shown, the Formula VI compound bears a butoxycarbonyl amine protecting group.
In some embodiments, the amine protecting group is an acid-cleavable protecting group.
In this equation, ProG2 represents an amine protecting group.
The amine protecting group PG4 can be removed to afford compound of general formula 1.
Preferably the nitrogen protecting group is an amine protecting group and / or an amide protecting group.
Removal of the amine protecting group provides the mono N-alkylated polymeric hydroxylamine resin compound 8.
Pg1 is a suitable amine protecting group.
Amine protecting group reagent ( s ) may be added to excess.
A preferred hydrogenation labile amine protecting group is benzyloxycarbonyl ( CBZ ).
Pg is an amine protecting group as defined previously, preferably trityl ( triphenylmethyl ).
The choice of alcohol used to prepare compound 35 determines the amine protecting group e . g.
PG ' represents a suitable amine protecting group such as phthalimide or benzyl and is preferably phthalimide.
In scheme 1, Rx is an appropriate amine protecting group.
A particularly useful amine protecting group for the synthesis of compounds of Formula ( I ) is the trifluoroacetamide.
In another specific embodiment of the thirty-fourth embodiment, P3 is an amine protecting group.
PG ′ represents a suitable amine protecting group such as benzyl or Boc.
In the subsequent text, Pg2 represents either hydrogen or an amine protecting group ProG2.
Boc or BOC refers to the Amine protecting group tert-Butyloxycarbonyl.
The amine protecting group may be changed at this stage, for example, to introduce a Boc-group.
Compound of formula ( II ), wherein P is an amine protecting group.
P1 is an amine protecting group such as one described previously under process ( b ).
In other embodiments, R4 is a monovalent amine protecting group.
PG of e is a suitable amine protecting group such as t-butylester ( BOC ).
In compounds of formula RuNHS ( O ) 2Cl, Ru may be hydrogen or an amine protecting group.
A preferred acid labile amine protecting group is tert - butoxycarbonyl ( BOC ).
Preferably R8 is hydrogen or lower alkyl and R9 is an amine protecting group.
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