Examples of 'hydroxyl protecting group' in a sentence
Meaning of "hydroxyl protecting group"
Hydroxyl protecting group - A hydroxyl protecting group is a chemical modification added to hydroxyl (OH) functional groups in organic molecules to prevent unwanted reactions at that site, allowing selective transformations elsewhere in the molecule
How to use "hydroxyl protecting group" in a sentence
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hydroxyl protecting group
Represents a hydrogen atom or a hydroxyl protecting group.
The hydroxyl protecting group may also be a silyl group.
The method used is tailored to the particular hydroxyl protecting group.
An example of a useful hydroxyl protecting group is a triisopropylsilyl moiety.
In the context of the present invention a preferred hydroxyl protecting group is benzyl.
P is a hydroxyl protecting group.
X is halo and PG is a suitable hydroxyl protecting group.
The hydroxyl protecting group used in this step is not particularly limited.
The hydroxy protecting group P can be any hydroxyl protecting group known in the art.
The hydroxyl protecting group is removed, and a chemically-active group is added.
A compound having the formula wherein P is a hydroxyl protecting group.
Removing the suitable hydroxyl protecting group to form a compound of formula La.
Oxidizing the cyclohexanol hydroxyl group and removing hydroxyl protecting group X.
Is H or a hydroxyl protecting group.
In one embodiment, the deprotecting reagent is a suitable reagent for deprotecting a phenolic hydroxyl protecting group.
See also
In certain embodiments, the hydroxyl protecting group is isopropyl.
Is H, a hydroxyl protecting group or a reactive phosphorus group as defined in claim 1 ;.
Step 5 is the introduction of hydroxyl protecting group.
Rs is a conventional hydroxyl protecting group such as those discussed below, for example para-bromobenzyl.
The process of claim 1 wherein the acid labile phenolic hydroxyl protecting group is tetrahydropyranyl.
Wherein R is a hydroxyl protecting group, followed by removal of the hydroxyl protecting group R.
In some embodiments, PG is a hydroxyl protecting group.
Is H, a hydroxyl protecting group or a reactive phosphorus group ;.
In certain embodiments, the hydroxyl protecting group is methyl.
Particularly preferred compounds of formula ( I ) are those wherein R ₁ respresent a hydroxyl protecting group.
In one embodiment, the hydroxyl protecting group may be benzyl.
A compound according to claim 1 of formula wherein Rc is a hydroxyl protecting group.
In another embodiment, the hydroxyl protecting group is a carbamate group.
In another embodiment, G in compounds of any of Formulae I-V is a hydroxyl protecting group PG.
In another embodiment, the hydroxyl protecting group is a carbonate group.
Which comprises reacting the azetidinone ( II ) wherein R1 is a hydroxyl protecting group.
In certain embodiments, the hydroxyl protecting group is methyl or isopropyl.
A process for the preparation of compounds of formula ( I ) wherein R1 is a hydroxyl protecting group.
Is selected from hydrogen, hydroxyl protecting group or hydroxyl activating group ;.
In certain embodiments, each of T1 and T2 is a hydroxyl protecting group.
In some embodiments, the hydroxyl protecting group may be cleaved under coupling conditions.
Hence, P represents hydrogen or a hydroxyl protecting group.
R1a is a hydroxyl protecting group.
In a more particularly preferred embodiment the R1 hydroxyl protecting group is benzyl.
R5 is a hydroxyl protecting group.
The method of any one of claims 1 to 6, wherein R5 is a hydroxyl protecting group representing benzoyl.
Preferably, the hydroxyl protecting group R is benzyl and 4-methoxybenzyl.
In one embodiment, P is hydroxyl protected by a hydroxyl protecting group as defined above.
The hydroxyl protecting group PG1 is as defined above for PG in Scheme 1.
In one embodiment of the invention, the hydroxyl protecting group is a silyl protecting group.
The bicyclic nucleoside of claim 1 wherein each of T1 and T2 is a hydroxyl protecting group.
PG3 is a suitable hydroxyl protecting group.
R13 is a phosphite ester protecting group ; and R14 is an acid-cleavable hydroxyl protecting group.
In another embodiment, the hydroxyl protecting group PG is a silyl group.
The oligomeric compound of any one of embodiments 16-31 wherein T4 is H or a hydroxyl protecting group.
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