Examples of 'antigen binding domain' in a sentence
Meaning of "antigen binding domain"
antigen binding domain: In biology and immunology, this phrase refers to the part of an antibody that binds to specific antigens, such as pathogens or foreign substances, triggering an immune response
How to use "antigen binding domain" in a sentence
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antigen binding domain
The antigen binding domain binds to EGFRvIII.
The term also covers any polypeptide or protein comprising an antigen binding domain.
The antigen binding domain comprises a leader sequence.
The package may be a bacteriophage which displays an antigen binding domain at its surface.
A functional antigen binding domain is capable of specifically binding to an antigen.
Recombinant immunotoxins selectively kill cells which are recognized by the antigen binding domain.
Wherein the antibody or antigen binding domain binds selectively to OPGbp.
The present invention generally provides a specific binding member comprising an antibody antigen binding domain.
An antigen binding domain may be provided by one or more antibody variable domains.
The portion of the CAR of the invention comprising the antigen binding domain targets EGFRvIII.
An antigen binding domain can comprise the extracellular domain of an inhibitory receptors.
Generally Vx and Vy together form an antigen binding domain.
An antigen specific antigen binding domain produced by the process as defined above is described.
Generally VH and VI together form an antigen binding domain.
The antigen binding domain and the polymerizing domain can be connected through a synthetic linker.
See also
Generally Vxx and Vyy together form an antigen binding domain.
The antigen binding domain may comprise a light chain variable region and a heavy chain variable region.
In an embodiment, the antigen binding domain is humanized.
In some aspects, the polypeptide further comprises an antigen binding domain.
An antibody or antigen binding domain which recognizes a DE epitope on human OPGbp.
The inter-chain disulfide bonds help bring together the two parts of the antigen binding domain.
An antigen specific antigen binding domain produced from a variable region of NAR is also described.
In some aspects, an IgG Fc variant domain containing polypeptide comprises an antigen binding domain.
In some embodiments, the antigen binding domain is a cytokine.
An antigen binding domain derived from an antibody against an antigen of the target, or.
In one aspect, the antigen binding domain is humanized.
In one example, the Fnl4-binding protein comprises an antibody antigen binding domain.
In embodiments, the antigen binding domain is a single polypeptide.
In an instance, each of the CARCD4 + and CARCD8 + comprises the same antigen binding domain.
In one aspect, the antigen binding domain binds to EGFRvIII.
The antigen binding domain may selectively bind a protein, carbohydrate, or sugar.
In several embodiments, the antigen binding domain can be a scFv.
An antigen binding domain can comprise a sequence from Table 2.
Generally, CARs comprise an extracellular antigen binding domain and an intracellular domain.
In an embodiment, the antigen binding domain binds a growth factor or hormone receptor.
In one instance, a KIR-CAR described herein comprises an antigen binding domain comprising an scFv.
In one instance, the antigen binding domain is a humanized antibody or antibody fragment.
In this connection, the antigen specific antigen binding domain is raised to a single antigen.
In one embodiment, the antigen binding domain is an antibody or an antigen-binding fragment thereof.
In an instance, the CARCD8 + comprises an antigen binding domain from Table 2.
In one instance, the antigen binding domain is a murine antibody or antibody fragment described herein.
In an instance, a FcR-CAR comprises an antigen binding domain and a FcR intracellular domain.
The antibody or antigen binding domain of Claims 1 or 2 which inhibits bone resorption.
The invention provides a CAR comprising an antigen binding domain of human antibody 139.
The antibody or antigen binding domain of Embodiments 1 or 2 which inhibits bone resorption.
In one embodiment, a TCAR comprises an antigen binding domain fused to an intracellular domain.
The antibody or antigen binding domain of claim 1 further comprising a human Fc region.
In one instance, said TCAR comprises an antigen binding domain and a primary stimulation domain.
One example of an antigen-binding domain is an antigen binding domain formed by a VH-VL dimer.
In an instance, a NCR-CAR comprises an antigen binding domain and a NCR transmembrane domain.
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