Examples of 'antigen binding site' in a sentence
Meaning of "antigen binding site"
antigen binding site: In immunology, this phrase refers to a specific region on an antibody where an antigen binds. This interaction is crucial for the immune system to identify and respond to foreign substances in the body
How to use "antigen binding site" in a sentence
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antigen binding site
They have apparently no antigen binding site.
The antigen binding site may be affinity matured.
An antibody fusión protein comprises at least one antigen binding site.
Six CDRs confer an antigen binding site to the antibody.
An antigen binding site disclosed herein can be administered on multiple occasions.
Antibody fragments generally include at least one antigen binding site.
The antigen binding site may have multiple specificities or valencies.
The unlabelled antibody serves as a competitor for the antigen binding site.
The antigen binding site of the IgE antibody binds to an autoantigen.
These domains contribute specificity and affinity of the antigen binding site.
Antigen binding site.
A single domain antibody comprises a single antigen binding site comprising a single domain.
The antigen binding site of the IgG antibody binds to the FceRI.
This work underlines the pivotal importance of the CDRs in forming an antigen binding site.
The viruses bind to the antigen binding site at the other end of the antibody.
See also
Substitutions may also be made to germline the antibody or stabilize the antigen binding site.
Other such antibodies combine a first antigen binding site with a binding site for a second antigen.
The variable domains are involved in antigen recognition and form the antigen binding site.
The antigen binding site of each HLA has genetic polymorphism.
Monovalent antibody fragments as meant in the present invention have only one antigen binding site.
The antigen binding site may be syngeneic, allogeneic or xenogeneic.
The system requires high affinity between the antigen binding site and the analyte.
A “ paratope ” is the antigen binding site that is specifically bound by an antibody.
Sequence operably linked to the DNA encoding an antigen binding site of the invention.
Also, a given antigen binding site may contain many types of modifications.
The framework region ligated to the CDR having a good antigen binding site is selected.
For example the first antigen binding site is directed to an angiogenesis receptor e . g.
Said VI and VH generally form the antigen binding site.
In one embodiment, the antigen binding site of the IgG antibody binds to the FceRI.
Generally, not bound through the antigen binding site.
Thus, the antigen binding site of the antibodies can not penetrate a groove or cavity.
Generally, not bound through the antigen binding site as defined above.
It has a molecular weight of approximately 50 kD and contains a single antigen binding site.
An antigen binding site may consist of an antibody VH domain and / or a VI domain.
A reshaped human antibody according to claim 1 comprising an antigen binding site comprising,.
Antibody, A molecule including an antigen binding site which specifically binds ( immunoreacts with ) an antigen.
As used herein, the term multivalent means more than one antigen binding site.
The antigen binding site is composed of six hypervariable regions ( a . k . a . complementarity determining regions ( CDRs ) ).
An antibody comprising the antigen binding portion or antigen binding site of the antibody under ( i ).
A particularly preferred antigen binding site comprises light chain CDRs 1-3 and heavy chain CDRs 1-3.
The variable regions of each light / heavy chain pair typically form the antigen binding site.
An F ( ab ' ) 2 molecule having a the antigen binding site of the monoclonal antibody of claim 1.
Thus, preferably, the antibody library has only those residues in the antigen binding site varied.
An antigen binding site for binding to a P2X7 receptor according to claim 1, wherein.
In some instances, framework residues of the antigen binding site may also be non human.
Generally, a VH domain is paired with a VL domain to provide an antibody antigen binding site.
Figure 4 depicts an electron density map of the antigen binding site of the F151 antibody / kallidin complex.
A " Fv " fragment is the smallest antibody fragment that retains an intact antigen binding site.
Generally, a sufficient antigen binding site requires CDR3 of the heavy chain ( CDRH3 ).
Therefore, IA-NBD is part of the antigen binding site.
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