Examples of 'antigen-binding site' in a sentence
Meaning of "antigen-binding site"
antigen-binding site: This phrase is a term used in biology to describe a specific region on an antibody that binds to an antigen
How to use "antigen-binding site" in a sentence
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antigen-binding site
The antigen-binding site is indicated by a triangle.
The hyperbariable regions for the antigen-binding site.
An antibody antigen-binding site may be provided by one or more antibody variable domains.
There are two general steps in veneering a murine antigen-binding site.
Six CDRs confer an antigen-binding site to the antibody.
These regions determine the specificity of the antigen-binding site.
Such residues might affect antigen-binding site and affinity directly or indirectly.
A binding member normally comprises a molecule having an antigen-binding site.
In some embodiments, an antigen-binding site is provided by one or more antibody variable regions.
These domains contribute specificity and affinity of the antigen-binding site.
In certain embodiments, an antibody comprises an antigen-binding site that specifically binds to a particular epitope.
That is, the heavy chain variable domain forms the complete antigen-binding site.
In some embodiments, an antibody comprises an antigen-binding site that specifically binds to a particular epitope.
The term also relates to any polypeptide or protein comprising an antibody antigen-binding site.
This is the binding site for antigen, the antigen-binding site or antibody combining site.
See also
The term also covers any polypeptide or protein comprising an antibody antigen-binding site.
The idiotype represents the highly variable antigen-binding site of an antibody and is itself immunogenic.
A binder may be an antibody molecule or a non-antibody protein that comprises an antigen-binding site.
Affinity is the interaction between a single antigen-binding site on an antibody molecule and a single epitope.
Thus, the molecular recognition units are primarily responsible for the specificity of an antigen-binding site.
Antibodies and binding compositions derived from an antigen-binding site of an antibody are disclosed.
A binding member according to the invention comprises an antibody molecule that comprises an antigen-binding site.
This approach has the advantage that the antigen-binding site remains unaffected.
The antigen-binding site of such antibodies is one single domain, referred to as VHH.
This conjugate is monovalent owing to the single scFv antigen-binding site per molecule.
Alternatively, the second antigen-binding site binds to a different epitope of AXL.
The variable region of each light-heavy chain pair forms an antigen-binding site of the antibody.
The antigen-binding site is formed by the hypervariable regions of a VH, VI pair.
Replacement of glutamine with proline would result in an antigen-binding site having different structure.
A first antigen-binding site that specifically binds human VEGF, and.
Anti-idiotypic antibodies recognize antigenic determinants associated with the antigen-binding site of another antibody.
The structure for carrying an antigen-binding site is typically an antibody VH or VI.
An immunoglobulin Fv fragment thus contains a single antigen-binding site.
A polypeptide including the antigen-binding site of an antibody according to claim 25.
The invention discloses the amino acid sequences of the responding antigen-binding site for this receptor.
The antigen-binding site is reduced to a single domain, the VHH domain, in these animals.
Generally, a VH domain is paired with a VL domain to provide an antibody antigen-binding site.
An antibody according to claim 9, wherein another antigen-binding site recognises a cytotoxic substance.
In general, a VH domain is paired with a VL domain to provide an antibody antigen-binding site.
A first antigen-binding site that specifically binds human vascular endothelial growth factor ( VEGF ), and.
FR can be selected in such a manner that CDR can form appropriate antigen-binding site.
An antibody of ( 9 ), wherein another antigen-binding site recognises a cytotoxic substance.
The N-termini of the light and heavy chains come together to form the antigen-binding site.
As first antigen-binding site binding to VEGF, e . g.
The V regions each contain 3 hypervariable regions that make up the antigen-binding site.
Alternatively, the second antigen-binding site binds to a different epitope of CD74.
An antigen-binding antibody comprises an antigen-binding site.
The so-called “ nanobodies ”, which harbour an antigen-binding site in a single Ig-like domain described e . g.
Fv fragments are typically about 25 kDa for and contain a complete antigen-binding site.
VH and VI make up the antigen-binding site.
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Examples of using Antigen-binding
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The antigen-binding protein may be an antibody
Variable regions confer antigen-binding specificity
Antigen-binding proteins are not limited to antibodies
