Examples of 'antisense compound' in a sentence
Meaning of "antisense compound"
antisense compound - An antisense compound is a type of molecule that can bind to complementary RNA or DNA sequences, affecting gene expression or function
How to use "antisense compound" in a sentence
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antisense compound
The antisense compound is an oligonucleotide targeting ApoCIII.
This may be done at any of the positions of the antisense compound.
The antisense compound is an antisense oligonucleotide.
Is a second antisense compound.
The antisense compound may comprise a modified nucleobase.
The disclosure is not limited by the method of antisense compound synthesis.
The antisense compound is to be administered to the subject in a therapeutic amount.
The invention is not limited by the method of antisense compound synthesis.
Targeting an antisense compound to a particular nucleic acid is a multistep process.
They have been selected as primary targets for antisense compound design.
One or more of such antisense compounds may be a short antisense compound.
This refers to the length of the antisense strand or portion of the antisense compound.
One or more of those antisense compounds may be a short antisense compound.
More preferably, the compound is an antisense compound.
Also disclosed herein is an antisense compound or composition as described above for medical use.
See also
In certain embodiments, the second compound is an antisense compound.
Preferably, the antisense compound is an antisense oligonucleotide.
In certain embodiments, the first compound is an antisense compound.
In certain embodiments, the antisense compound is a modified oligonucleotide.
In certain embodiments, the nucleic acid is an antisense compound.
In certain embodiments, the antisense compound is an antisense oligonucleotide.
In some instances, the second compound is an antisense compound.
In other embodiments, the antisense compound is an antisense oligonucleotide.
In some instances, the first compound is an antisense compound.
In certain embodiments, an antisense compound includes one mismatch.
In certain embodiments, the second agent is a second antisense compound.
In certain embodiments, the antisense compound reduces inflammation.
In certain such methods, the nucleic acid is an antisense compound.
In certain embodiments, an antisense compound includes two mismatches.
In some embodiments, the test compound comprises an antisense compound.
In some embodiments, the antisense compound is an antisense oligonucleotide.
In certain embodiments, a portion is a defined number of contiguous nucleobases of an antisense compound.
In some embodiments of the invention the antisense compound contains chemical modifications.
The antisense compound may be a single-stranded or double-stranded oligonucleotide.
In certain instances the pharmaceutical agent in an antisense compound as further described herein.
Preferably, an antisense compound is targeted to one or more specific connexin isotypes.
In certain embodiments, for example, the antisense compound reduces inflammation.
The antisense compound is an antisense oligonucleotide, and the linked subunits are nucleotides.
In certain embodiments, the antisense compound is a salt form.
In certain instances of the disclosure, the nucleic acid is an antisense compound.
In certain instances, the antisense compound is an antisense oligonucleotide.
A “ portion ” can also refer to a defined number of contiguous nucleobases of an antisense compound.
In certain embodiments, the antisense compound is parenterally administered.
The antisense compound of claim 5, wherein the antisense oligonucleotide is an oligonucleotide mimetic compound.
In certain embodiments, the antisense compound is also administered systemically.
In certain embodiments, the modified internucleoside linkages are interspersed throughout the antisense compound.
In certain embodiments, an antisense compound includes three or more mismatches.
Such administration, may, in some embodiments, substantially avoid unwanted systemic absorption of the antisense compound.
In certain embodiments, an antisense compound administered systemically enters neurons.
In certain instances of the disclosure, the nucleic acid is an antisense compound targeting ApoCIII.
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Examples of using Antisense
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Antisense RNAs can be classified in different ways
In a separate embodiment new antisense oligodeoxynucleotides are provided
Antisense polynucleotides can include deoxyribonucleotides or ribonucleotides
Examples of using Compound
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