Examples of 'antisense compounds' in a sentence
Meaning of "antisense compounds"
Antisense compounds are synthetic nucleic acids or nucleic acid analogs that are designed to bind to specific mRNA molecules and inhibit their function. They work by preventing mRNA from being translated into proteins, thereby reducing the production of a specific protein in the body. Antisense compounds have potential therapeutic applications in gene regulation and the treatment of genetic diseases
How to use "antisense compounds" in a sentence
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antisense compounds
Cell culture and antisense compounds treatment.
Phosphorothioate linkages provide several properties to antisense compounds.
Selective antisense compounds and uses thereof.
Conjugate groups may be attached directly to antisense compounds or by use of a linker.
The short antisense compounds comprise a conjugate group.
In vivo testing of antisense compounds.
Antisense compounds are commonly used as research reagents and diagnostics.
Numerous examples of antisense compounds are known in the art.
Antisense compounds can exert their effect by a variety of means.
Also disclosed herein are antisense compounds that are chimeric compounds.
All antisense compounds comprise phosphorothioate linkages at each position.
The present invention also includes antisense compounds which are chimeric compounds.
The antisense compounds may be administered in a pharmaceutically acceptable carrier.
The present invention also includes antisense compounds that are chimeric compounds.
Antisense compounds comprising a variety of chemical modifications and motifs have been reported.
See also
Certain embodiments provide antisense compounds targeted to a huntingtin nucleic acid.
Antisense compounds targeted to such variants are within the scope of the instant invention.
Pharmaceutical and other compositions comprising the antisense compounds of the invention are also provided.
Two or more antisense compounds may be used together or sequentially.
Method for reducing scarring during wound healing using antisense compounds directed to ctgf.
Also provided are antisense compounds targeted to cis regulatory elements.
Combinations Compositions of the disclosure can contain two or more antisense compounds.
Disclosed herein are antisense compounds targeted to a huntingtin nucleic acid.
Pharmaceutical Compositions Also described are pharmaceutical compositions comprising antisense compounds.
Also disclosed are antisense compounds targeted to cis regulatory elements.
In certain embodiments, oligomeric compounds are antisense compounds.
One or more of such antisense compounds may be a short antisense compound.
In certain embodiments, chimeric compounds are short antisense compounds.
One or more of those antisense compounds may be a short antisense compound.
In some embodiments, test compounds include antisense compounds.
Any of the antisense compounds described herein can have a gapmer motif.
Polynucleotide and nucleic acid connexin inhibitors Antisense compounds may also be used in certain embodiments.
The antisense compounds provided herein can be include in a pharmaceutical composition or formulation.
Certain embodiments provide antisense compounds targeted to a CFB nucleic acid.
Antisense compounds useful in the methods of the present disclosure include chimeric oligonucleotides.
Certain embodiments provide antisense compounds targeted to a GCGR nucleic acid.
Antisense compounds can be synthesized using any suitable methods known in the art.
Certain embodiments disclose antisense compounds targeted to a GCGR nucleic acid.
Antisense compounds and methods of using them are also provided by the present invention.
In certain instances, conjugated antisense compounds are prodrugs.
Antisense compounds targeted to a huntingtin nucleic acid comprise one or more modified internucleoside linkages.
In certain embodiments, short antisense compounds are gapmers.
Antisense compounds for modulating expression of huntingtin are disclosed in the aforementioned published patent applications.
In certain embodiments, conjugated antisense compounds are prodrugs.
Also described are antisense compounds and methods for reducing tissue damage associated with ophthalmic procedures.
In certain embodiments, conjugated antisense compounds are well tolerated.
Active antisense compounds are those that modulate the expression of their target RNA.
In certain embodiments, conjugated antisense compounds are administered to a subject.
Several antisense compounds are now in clinical trials in the United States.
In certain embodiments, conjugated antisense compounds accumulate in the liver.
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Examples of using Antisense
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Antisense RNAs can be classified in different ways
In a separate embodiment new antisense oligodeoxynucleotides are provided
Antisense polynucleotides can include deoxyribonucleotides or ribonucleotides
Examples of using Compounds
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These compounds are not effective against spores
Delete volatile organic compounds content of products
These compounds are now under further investigation
