Examples of 'apoptotic pathway' in a sentence
Meaning of "apoptotic pathway"
apoptotic pathway: a series of molecular signaling events that lead to programmed cell death, known as apoptosis. This phrase is frequently used in the field of biology, specifically in the study of cell processes and mechanisms related to cell death
How to use "apoptotic pathway" in a sentence
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apoptotic pathway
The caspases are an integral part of the apoptotic pathway.
Defects in the apoptotic pathway may contribute to the onset or progression of malignancies.
These compounds did not induce the extrinsic apoptotic pathway.
They can trigger the apoptotic pathway and are available for treatment of blood disorders.
Antibodies to the receptor can be agonists or antagonists of the apoptotic pathway.
Potential Sulindac activation of the extrinsic apoptotic pathway resulted in Bax activation was also examined.
Previous studies have established that Bax induces mitochondrial apoptotic pathway.
It is also involved in an apoptotic pathway characterized by activation of caspase-6.
Essentially these work by mimicking key interactions that activate apoptotic pathway in the cell.
Cysteine proteases ( caspases ) are central to the apoptotic pathway and are expressed as inactive zymogens.
Certain cells and viruses produce anti-apoptotic genes that function in the mitochondrial apoptotic pathway.
Thus, neither the mitochondrial nor the endoplasmic apoptotic pathway was fully activated.
The Bcl-2 family proteins act as an intracellular checkpoint in the apoptotic pathway.
However, the mechanism by which such damage induced the apoptotic pathway remained unclear.
Thus, taurultam is able to enhance the effectiveness of the Fas-ligand induced apoptotic pathway.
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Bortezomib activates the mitochondrial-based apoptotic pathway Pei et al.
Furthermore, we have provided evidence that . apoptin is distinct from the p53-induced apoptotic pathway.
GAS1 induces cell death through an intrinsic apoptotic pathway.
Aloe-emodin induces apoptosis in T24 human bladder cancer cells through the p53 dependent apoptotic pathway.
The inter-relationship between the activities of the various caspases in this apoptotic pathway is complex.
FasL / Fas receptor-mediated CTL injury initiates target cell death vía a Ca2+-independent apoptotic pathway.
Figure 6 shows the activation of a TNFa-induced extrinsic apoptotic pathway by Sulindac.
FasL is one of the major triggers of the caspase-8 activated extrinsic apoptotic pathway.
FIGS . 6A-6I show the activation of a TNFa-induced extrinsic apoptotic pathway by Sulindac.
They found that the extract activates JNK, a protein that regulates the apoptotic pathway.
Figure 6 Schematic way of Survivin in the apoptotic pathway.
Thus, Sulindac / TNFa-induced apoptosis is mediated by the extrinsic apoptotic pathway.
Inhibition of bcl-2 function prevents inactivation of Bax, and allows the apoptotic pathway to proceed.
The oncogene bcl-2 functions by binding and inactivating Bax, a protein in the apoptotic pathway.
It indicates activation of the p53-independent apoptotic pathway.
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Examples of using Pathway
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The first pathway is the most relevant
Family migration as an alternative pathway for refugees
Pathway descriptions begin on the following page
Examples of using Apoptotic
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Apoptotic cells were determined by using TdT staining
After detection the apoptotic cells are removed
Apoptotic processes are associated with multiple sclerosis
