Examples of 'biallelic' in a sentence
Meaning of "biallelic"
Biallelic refers to a genetic condition or trait that is associated with having two different alleles at a particular gene locus
Show more definitions
- Of or pertaining to both alleles of a gene (in a heterozygote).
How to use "biallelic" in a sentence
Basic
Advanced
biallelic
Usually a biallelic marker is a single nucleotide polymorphism.
Genetic analysis of these additional biallelic markers is performed as follows.
A biallelic polymorphism has two forms.
The invention also describes sets of these biallelic markers.
The biallelic markers are localized as follows.
Those amplification products which contained biallelic markers were identified.
The biallelic markers were then used in association studies.
The frequency of resulting monoallelic and biallelic mutations was then assessed.
A biallelic polymorphism has two alleles.
Platelet alloantigens result from biallelic polymorphisms of membrane glycoproteins of platelets.
Biallelic targeting was observed in one colony.
Oligonucleotide probes may be used in genotyping biallelic markers by hybridization assays.
The biallelic markers were then used in association studies as described below.
Determining the proportional representation of said biallelic marker in said population.
Genotype calling for biallelic SNPs is traditionally done by clustering.
See also
Association studies have most usually relied on the use of biallelic markers.
Biallelic markers generally consist of a polymorphism at one single base position.
The diagnostics may be based on a single biallelic marker or a on group of biallelic markers.
The biallelic markers may be identified using the techniques described herein.
Such primers are able to discriminate between the two alleles of a biallelic marker.
Interrogating closely adjacent biallelic SNPs across the chromosome of the target cell.
Biallelic sites were systematically verified by comparing the sequences of both strands of each pool.
The methods described herein promote and increase the frequency of biallelic modifications.
The genetic analysis using the biallelic markers disclosed may be conducted on any scale.
Most of these polymorphic sites are generated by single base substitution mutations and are biallelic.
The combined effects of these advantages make biallelic markers extremely valuable in genetic studies.
Biallelic markers disclosed can be used to demonstrate that a candidate gene is associated with a trait.
The invention further encompasses biallelic markers of the CanIon gene useful in genetic analysis.
Sequence analysis allows the identification of the base present at the biallelic marker site.
The positions of the biallelic markers along chromosomes may be determined using a variety of methodologies.
A cell having the modified genome comprising the biallelic modification can then be identified.
The methods of the present invention involve performing haplotype analyses on groups of biallelic markers.
Biallelic markers have been identified in the genomic sequence of FLAP.
The mutation detection procedure is essentially similar to that used for biallelic marker identification.
Biallelic pathogenic variants in GAMT are the underlying cause of the disorder.
The mutation detection procedure is essentially similar to that used for biallelic site identification.
AR is the risk attributable to a biallelic marker allele or a biallelic marker haplotype.
PCR assays are performed with primers defining the biallelic marker.
The target DNA comprising a biallelic marker may be amplified prior to the hybridization reaction.
PCR technology is the preferred amplification technique used to identify new biallelic markers.
Biallelic marker Original allele.
In some methods, the targeted genetic modification is biallelic.
A portion of the biallelic markers of the present invention are disclosed in Tables A and B.
The invention also concerns FLAP-related biallelic markers.
Biallelic markers are genome-derived polynucleotides which exhibit biallelic polymorphism.
The method of embodiment 1, wherein the targeted genetic modification is biallelic.
The biallelic markers is used in linkage analysis and in allele-sharing methods.
In this embodiment, each haplotype comprises a group of three biallelic markers.
In particularly preferred probes, the biallelic marker is at the center of said polynucleotide.
For example, each group may comprise three biallelic markers.
