Examples of 'biallelic markers' in a sentence
Meaning of "biallelic markers"
Biallelic markers: Genetic markers with two possible alleles at a specific locus. They are commonly used in genetic research to assess variations in DNA sequences
How to use "biallelic markers" in a sentence
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biallelic markers
The biallelic markers are localized as follows.
Genetic analysis of these additional biallelic markers is performed as follows.
The biallelic markers were then used in association studies.
The invention also describes sets of these biallelic markers.
The biallelic markers were then used in association studies as described below.
Those amplification products which contained biallelic markers were identified.
Biallelic markers generally consist of a polymorphism at one single base position.
Oligonucleotide probes may be used in genotyping biallelic markers by hybridization assays.
The biallelic markers may be identified using the techniques described herein.
Association studies have most usually relied on the use of biallelic markers.
The genetic analysis using the biallelic markers disclosed may be conducted on any scale.
The diagnostics may be based on a single biallelic marker or a on group of biallelic markers.
The combined effects of these advantages make biallelic markers extremely valuable in genetic studies.
Biallelic markers disclosed can be used to demonstrate that a candidate gene is associated with a trait.
The invention further encompasses biallelic markers of the CanIon gene useful in genetic analysis.
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The methods of the present invention involve performing haplotype analyses on groups of biallelic markers.
The positions of the biallelic markers along chromosomes may be determined using a variety of methodologies.
PCR technology is the preferred amplification technique used to identify new biallelic markers.
Biallelic markers have been identified in the genomic sequence of FLAP.
The invention also concerns FLAP-related biallelic markers.
A portion of the biallelic markers of the present invention are disclosed in Tables A and B.
In this embodiment, each haplotype comprises a group of three biallelic markers.
Biallelic markers are genome-derived polynucleotides which exhibit biallelic polymorphism.
For example, each group may comprise three biallelic markers.
The biallelic markers is used in linkage analysis and in allele-sharing methods.
Such a method may also be performed for a combination of more than 2 biallelic markers.
Alternatively, biallelic markers inside noncoding exons or inside introns may be used.
The above procedure permits those amplification products, which contain biallelic markers to be identified.
In some embodiments, biallelic markers which lie within coding regions may be used.
Using such procedures, a number of BAC clones carrying selected biallelic markers can be isolated.
The biallelic markers may be used in parametric and non-parametric linkage analysis methods.
The invention also concerns FLAP-related biallelic markers which are in association with asthma.
Biallelic markers are genome-derived polynucleotides that exhibit biallelic polymorphism at one single base position.
In a highly preferred embodiment, the biallelic markers span the entire candidate genomic region.
The first column of Figure 6A lists the BAC clones in which the biallelic markers lie.
In a first embodiment, biallelic markers are identified using genomic sequence information generated by the inventors.
Example 15 below describes the identification of sets of biallelic markers within the candidate genomic region.
The localization of biallelic markers on BAC clones is performed essentially as described in Example 2.
The present invention also encompasses biallelic markers of the APM1 gene.
The frequencies of the biallelic markers in each population were determined as described in Example 17.
Having sequence fragments longer than 2.5 or 3kb enhances the chances of identifying biallelic markers therein.
The localization of the biallelic markers was as shown in Table 2.
These 500 bp fragments are amplified from genomic DNA and are scanned for biallelic markers.
The localization of these biallelic markers are as shown in Table 2.
The DNA from 100 individuals was extracted and tested for the detection of the biallelic markers.
The localization of these biallelic markers is as shown in Table 2.
These biallelic markers may all be KCNQ2-related biallelic markers.
Figure 9 shows the locations of the biallelic markers along the BAC contig.
APM1-related Biallelic Markers Biallelic markers generally consist of a polymorphism at one single base position.
The pooled DNA samples can be used to identify biallelic markers as described in Example 6.
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Examples of using Biallelic
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Usually a biallelic marker is a single nucleotide polymorphism
Genetic analysis of these additional biallelic markers is performed as follows
A biallelic polymorphism has two forms
Examples of using Markers
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No markers indicate that it was signed under duress
Superimposed hour markers with luminous dots
The markers should now be read automatically