Examples of 'c-jun' in a sentence
Meaning of "c-jun"
C-jun is a noun referring to a specific gene that plays a role in cell growth and division, often studied in molecular biology and genetics. For example, 'The researchers observed the expression of c-jun in the cancer cells.'
How to use "c-jun" in a sentence
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c-jun
The c-Jun mutants were expressed in similar amounts.
This analysis included all the isoforms of c-Jun.
The activity of c-Jun is regulated by phosphorylation.
Activation of MLKs can also induce c-Jun phosphorylation.
A similar procedure was followed to determine the mRNA content relative to C-Jun.
The synergistic induction of c-jun by both costimulatory paradigms was partially inhibited by CsA.
Therefore sensitivity to CsA is unique to c-jun.
Numbers indicate the amino acids of c-Jun present in each fusiĂłn protein.
Activation can also be detected with the substrate c-Jun.
Transcription of both c-fos and c-jun is induced rapidly and transiently following stimulation.
The migration positions of GSTcJun and c-Jun are indicated.
Antibodies specific for c-Jun protected NGF-deprived rat sympathetic neurones from apoptosis.
Within the short time frame of this experiment, there were minimal effects on c-Jun expression.
The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription.
JNK thus mediates the effect of extracellular stimuli on c-Jun.
See also
C-Jun is activated by JNKs, which phosphorylate its transcriptional activation domain.
Elution of JNK was examined by its ability to phosphorylate recombinant c-Jun in solution.
The linker sequence between the TCR and c-jun sequences is indicated in small letters.
Preferably the probe for identification of a cell with JNK kinase activity is a c-Jun protein.
The induction of c-jun by shear stress involved protein kinase C and endothelial NO synthase.
An enzymatically functional polypeptide or fragment of JNK possesses c-Jun N-terminal activation domain kinase activity.
This suggests that after phosphorylating GSTcJun, JNK dissociates from it and phosphorylates exogenous c-Jun.
Inhibition of c-JUN Phosphorylation by Activated JNKs.
JNK can translocate to the nucleus and activates transcription factors such as c-Jun and ATF2.
In unstimulated cells, phosphorylated c-Jun migrated as a single band.
The Western blot analysis shows the basal and phosphorylated forms of both JNK and c-Jun.
The c-Jun bands are indicated.
JNK translocates to the nucleus and activates transcription factors such as c-Jun and ATF2.
The c-Jun band is indicated.
Pathway convergence is at the level of c-fos and c-jun translation.
The levels of nf-Îşb and c-jun were measured in csf by dot blot assays.
Preferably, this protein kinase is a c-Jun Kinase.
In this case, the c-Jun and v-Jun lanes represent equal autoradiographic exposures.
In this case, the glucocorticoid receptor represses c-Jun activity, and the opposite is also observed.
Onc is a generic placeholder for a given specific oncogene, such as C-jun.
Those results indicate that c-jun antagonizes the proapoptotic activity of p53 in liver tumor.
Similar results were obtained with the AP-1 responsive c-jun promoter.
One particularly interesting kinase family are the c-Jun NH2-terminal protein kinases, also known as JNKs.
To elevate c-Jun expression, Jurkat cells were transfected with a c-Jun expression vector.
FIG . 6 is an illustration demonstrating the inhibition of c-Jun phosphorylation by activated JNKs.
Phosphorylation of c-Jun ( indicted by the arrow ) was analyzed by SDS-PAGE and autoradiography.
FIGURE 10 shows the nucleotide and deduced amino acid sequence of c-Jun.
A method for identifying a composition which affects the c-Jun N-terminal kinase of claim 1 or 2 which comprises,.
As can be seen from Table 7, VEGF treatment of HUVECs caused an increase of c-Jun.
The TAT-IBpeptides efficiently prevented phosphorylation of c-Jun by activated JNKs in these experiments… See, FIG.
Cell activation was visualized by the expression of the AP-1 transcription promoters c-Fos and c-Jun.
C, As b, but phosphorylation of c-Jun induced by TNF or UV stress.
AU-rich elements also regulate the biosynthesis of proto-oncogenic transcription factors like c-Jun and c-Fos.
Phosphorylating the c-Jun N-terminal activation domain ;.
The present inventors have provided compounds, which are inhibitors of c-Jun N-terminal kinases.
