Examples of 'chiral acid' in a sentence
Meaning of "chiral acid"
chiral acid: Chiral acid is a type of acid that exhibits chirality, meaning that it cannot be superimposed on its mirror image. These acids have different chemical properties depending on their spatial arrangement, making them important in asymmetric synthesis
How to use "chiral acid" in a sentence
Basic
Advanced
chiral acid
The most preferred chiral acid is mandelic acid.
A chiral acid or base.
Resolution by recrystallization subsequent to conversion into a salt with a chiral acid.
It is preferred that the chiral acid be in a substantially optically pure state.
Preferably it is resolved by crystallisation in the presence of a single enantiomer of a chiral acid.
Which enantiomer of chiral acid is chosen depends on which enantiomer of narwedine is required.
The two enantiomers obtained are subsequently separated in a conventional manner using a chiral acid.
Indeed the chiral acid could be recovered as its salt using a strong base.
This is cleaved into the diastereomerically pure bicycles by salt formation with a chiral acid.
The chiral acid can be easily separated from the undesired nitrile as described below.
The enrichment process is carried out in a solution comprising the enantiomers and the chiral acid.
Preferably the chiral acid used in the process according to the invention is D tartaric acid.
Racemic compound VII is then crystallized with a chiral acid as described above.
The racemic methylphenidate, chiral acid and base may further be introduced independently of one another.
This may be accomplished by dissolving compound Ib and the chiral acid in refluxing methanol.
See also
Salt formation of 28 with a chiral acid affords a mixture of diastereomeric salts of formula 73.
In another embodiment, the acid is a chiral acid.
In some embodiments, the chiral acid is ditoluoyl tartaric acid.
In other embodiments, a substoichiometric amount of chiral acid is added.
In certain embodiments, the chiral acid is ditoluoyl-D-tartaric acid.
A process according to any preceding claim, wherein the resolution is conducted using a chiral acid.
The crystalline product VII . chiral acid is isolated by filtration.
Compounds of formula ( 1 ) and entantiomerically pure monobasic salts with pharmaceutically acceptable chiral acid thereof, wherein,.
In other embodiments, the chiral acid is ditoluoyl-L-tartaric acid.
In certain embodiments, an equimolar amount of chiral acid is added.
The ester 11 was saponified to the chiral acid 3 by lithium hydroxide and hydrogen peroxide treatment.
Neutralization and extractive work-up provides diastereomerically pure amino-tetrahydrofuran, 1, and recovery of the chiral acid.
The resolution step ( i ) is achieved with a suitable chiral acid in a suitable solvent.
A process of claim 3 wherein the chiral acid is 1R 10-camphorsulfonic acid, or R mandelic acid.
Alternatively, a mixture of diastereoisomeric compounds is treated with a chiral acid operable to form a salt therewith.
In advantageous embodiments the chiral acid is di-p-toluoyl-D-tartaric acid.
Separating the enantiomers of compounds of Formula 2B by chiral acid resolution or chiral chromatography.
It is also disclosed that the chiral acid is 1R 10-camphorsulfonic acid.
You'll also be interested in:
Examples of using Chiral
Show more
An object that is not chiral is said to be achiral
Such chiral diols are important in organic synthesis
Many electrophiles are chiral and optically stable
Examples of using Acid
Show more
Put citric acid in the inner container
He later admitted that he did it while tripping on acid
I was so busy pissing acid on that little shit
