Examples of 'chiral auxiliary' in a sentence
Meaning of "chiral auxiliary"
chiral auxiliary: In organic chemistry, a chiral auxiliary is a stereogenic group or molecule added to a reaction to control the stereochemistry of the products. It helps in the formation of chiral compounds with the desired spatial arrangement of atoms
How to use "chiral auxiliary" in a sentence
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chiral auxiliary
A chiral auxiliary may simultaneously function as a protecting group.
The reaction is performed in the presence of a chiral auxiliary.
The chiral auxiliary forms a white crystalline precipitate.
The reduction may be facilitated by the use of a chiral auxiliary.
The chiral auxiliary mediates the catalytic process.
The organic synthesis is an illustration of asymmetric synthesis via a chiral auxiliary.
The sulfinyl chiral auxiliary is readily removed by simple acid hydrolysis.
The individual enantiomers may be separated by use of a chiral auxiliary on nitrogen.
Evans chiral auxiliary.
Process for preparing matrix metalloproteinase inhibitors and chiral auxiliary therefor.
The chiral auxiliary may also be removed under reductive conditions.
The compound is chemically contaminated with small amounts of the chiral auxiliary.
Removal of the chiral auxiliary leads to the desired succinate analog.
The chiral reagent becomes attached to the condensed intermediate as a chiral auxiliary group.
Some chiral auxiliary was recovered by flushing the silica pad with methanol.
See also
The process can be easily scaled up and allows the recycling of the chiral auxiliary.
Other chiral auxiliary groups are also known in the art and may also be employed.
Camphorsultam also acts as a chiral auxiliary in Michael addition.
A preferred chiral auxiliary is See the example below for typical reaction conditions.
TLC analysis revealed the presence of unreacted chiral auxiliary in addition to the required product.
Removing the chiral auxiliary with aqueous acid and tetrahydrofuran to give the aldehyde.
The first step of Flow Sheet A is introduction of the chiral auxiliary.
The process makes use of a chiral auxiliary attached to the nitrogen of the morpholine ring.
Recrystallization from hexane / EtOAc yielded the chiral auxiliary as needles.
Hydrolysis of the chiral auxiliary gives a carboxylic acid III.
The selected cis - or the trans - isomer may then be chemically resolved using a chiral auxiliary.
Reductive removal of the chiral auxiliary then affords the homochiral alcohols of formula XXVIII.
The individual enantiomers of formula ( II ) can be separated using a chiral auxiliary.
Xc is a chiral auxiliary selected from the group comprising,.
Further, the amino protecting chiral auxiliary remains intact.
The chiral auxiliary agent is typically a compound of formula,.
The unsaturated ester 4a is then reacted with a chiral auxiliary to give the acceptor 5a.
Frequently, the chiral auxiliary can be recovered and used again.
In some embodiments, Rd is a chiral auxiliary group.
The chiral auxiliary was cleaved in an acidic medium according to the following protocol,.
In one embodiment, the acid used when reacting a chiral auxiliary is a Lewis acid.
In the case of a chiral auxiliary moiety, it can then be removed.
Advantageously when Pearlman 's catalyst is used the removal of the chiral auxiliary is most efficient.
The use of a chiral auxiliary may assist control of absolute and / or relative stereochemistry.
A separation of the enantiomers may be achieved e.g. by chiral auxiliary groups.
This route makes use of a chiral auxiliary and gives 9 in enantiomerically pure form.
The stereochemical model ( R)-10 of the key uricolytic intermediate was prepared using menthol as chiral auxiliary.
Condensing a chiral auxiliary with an aldehyde or ketone ; adding a nucleophile to the condensed product ; and.
A process according to Claim 1 wherein the chiral auxiliary group is derived from a chiral alcohol.
The chiral auxiliary can be recovered from the above described conversion step and reused / recycled.
The process of claim 1, wherein the chiral auxiliary is R tertiarybutylsulfinamide.
The above chiral auxiliary is synthesized in seven steps from L-phenylglycine.
The process of item 1, wherein the chiral auxiliary is a sulfonamide.
Hydrolysis of the chiral auxiliary with lithium hydroxide and hydrogen peroxide yields the carboxylic acid 19.
A process as claimed in claim 6 wherein R4 represents a chiral auxiliary.
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Examples of using Chiral
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An object that is not chiral is said to be achiral
Such chiral diols are important in organic synthesis
Many electrophiles are chiral and optically stable
Examples of using Auxiliary
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Call in auxiliary cops if you have them
The incoming hole diameter on auxiliary terminal
Auxiliary contacts and failure signal units
