Examples of 'cleavable linker' in a sentence
Meaning of "cleavable linker"
cleavable linker - In chemistry and biochemistry, a cleavable linker is a chemical compound or bridge that can be selectively and reversibly broken apart under certain conditions. It is often used in the design of molecules, drugs, or materials to facilitate controlled release or detachment of specific components
How to use "cleavable linker" in a sentence
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cleavable linker
In some aspects a biMab comprises cleavable linker.
A number of different cleavable linker groups have been described.
One or more linkers can be a cleavable linker.
Various cleavable linker chemistries are known in the art.
The linkers can be a cleavable linker.
Said cleavable linker may comprise a disulfide bond.
Conjugates also can be formed with a cleavable linker.
The value of having a cleavable linker is not considered.
A moiety may also be joined to a strand vía a cleavable linker.
X is a cleavable linker that is cleavable under physiological conditions.
The one or more linkers may be a cleavable linker.
A cleavable linker is typically susceptible to cleavage under intracellular conditions.
In a particular embodiment the linker may be a cleavable linker.
A peptide based cleavable linker comprises two or more amino acids.
A black dot indicates a cleavable linker.
See also
The core of the cleavable linker comprises a phenyl vinyl sulphone.
The latter requires that the linker is a cleavable linker.
The cleavable linker region may be one that is targeted by endocellular proteases.
A proportion of peptide on each bead is linked with a cleavable linker.
The cleavable linker may be any of the cleavable linkers described herein above.
The cephalosporin backbone serves as a cleavable linker between two dyes.
The cleavable linker is useful if subsequent removal of the affinity purification tags is desirable.
The antibody molecule may be conjugated to the bioactive molecule by a cleavable linker.
Markers produced after cleavage of the cleavable linker have a wide range of structure.
Cleavable linkers are cleavable under conditions wherein a selectively cleavable linker is not cleavable.
The two regions of the chimaeric antibody may be connected vía a cleavable linker sequence.
A selectively cleavable linker connecting a handle for purification and the reactive chemical unit is included.
The two regions of the chimeric antibody may be connected vía a cleavable linker sequence.
A cleavable linker X suitable for the practice of the invention may be a flexible linker.
The specific binding member may be conjugated to the bioactive molecule by a cleavable linker.
Sheffield did not use or suggest to use a cleavable linker between FIX and albumin.
The mobility modifier and detectable reporter are linked to the binding moiety by a cleavable linker.
A cleavable linker X is preferably cleavable under physiological conditions.
The above described fusión protein may further comprise a cleavable linker or cleavage site for proteinases.
The cleavable linker group I is not particularly limited.
The above mentioned fusión protein may further comprise a cleavable linker or cleavage site for proteinases.
A cleavable linker X may be configured for cleavage exterior to a cell.
Preferably, the linking reagent is a cleavable linker.
In one embodiment, this cleavable linker is a photocleavable linker.
In one aspect, the linker is a cleavable linker.
In some embodiments, the cleavable linker comprises a photocleavable linker.
In certain embodiments, the linker is a cleavable linker.
In this example, no cleavable linker is indicated.
In one embodiment, the linking reagent is a cleavable linker.
In one embodiment, the cleavable linker is hydrolyzed by an esterase enzyme.
In one embodiment, the linker is a cleavable linker.
However, the use of cleavable linker peptides is not suggested.
In some embodiments, the linker is a cleavable linker.
Linker is referred to cleavable linker and non-cleavable linker.
Hyperbranched polymer conjugates vía non-enzymatic cleavable linker.
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Examples of using Cleavable
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Other cleavable linkers require hydrogenolysis or photolysis
Suitable proteolytically cleavable linkers are described above
Such cleavable fluorogenic substrates are commercially available
Examples of using Linker
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Additional linker flags for this target
These two domains are connected by a flexible linker
Such linker peptides are considered to be of human origin
