Examples of 'cleavable linkers' in a sentence
Meaning of "cleavable linkers"
cleavable linkers: Cleavable linkers are molecules or compounds used in chemistry or biochemistry that can be selectively or specifically broken or cleaved under certain conditions to release a desired component or substance.
How to use "cleavable linkers" in a sentence
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cleavable linkers
Other cleavable linkers require hydrogenolysis or photolysis.
Suitable proteolytically cleavable linkers are described above.
Cleavable linkers are well known in the art.
An alternative to photocleavable linkers are enzyme cleavable linkers.
Cleavable linkers and protection groups.
Additional suitable cleavable linkers include disulfide linkers.
Another class of suitable linkers comprises cleavable linkers.
A variety of cleavable linkers are known in the art.
This covers a variety of photocleavable and chemically cleavable linkers.
Preferred cleavable linkers appear to be chemically or enzymatically cleavable.
The design of the interfaz is dependent on the choice of cleavable linkers.
Further suitable cleavable linkers include disulfide linkers.
Oligomers can be covalently derivatized to moieties that facilitate cell association using cleavable linkers.
Cleavable linkers can be selected from a variety chemical structures.
The cleavable linker may be any of the cleavable linkers described herein above.
See also
Cleavable linkers may be used.
The second object using iminosydnones as cleavable linkers we considered was an ADC.
Cleavable linkers should be flexible enough to allow cleavage by proteases.
In a certain embodiment, cleavable linkers may be used.
Other cleavable linkers are linkers capable of attaching to primary alcohol groups.
In some other such embodiments, the linkers are cleavable linkers.
A number of different cleavable linkers are known to those of skill in the art.
In addition to the linkers described above, selectively cleavable linkers may be employed.
The cleavable linkers may be selected from a large plethora of chemical structures.
Thus, cytotoxic conjugates linked vÃa disulfide-containing cleavable linkers have been sought.
Cleavable linkers of particular interest are currently linkers that can be cleaved by light.
The linkers used in the compositions of the invention are non-enzymatically cleavable linkers.
Cleavable linkers are cleavable under conditions wherein a selectively cleavable linker is not cleavable.
The use of bifunctional, multifunctional and / or cleavable linkers may also be desirable for certain applications.
Cleavable linkers may also be used in the compositions and methods described herein.
A person of ordinary skill in the art would readily distinguish non-cleavable from cleavable linkers.
Various known cleavable linkers can be used to monitor the solid phase sequential ligations.
Suitable linking groups are well known in the art and include non-cleavable or cleavable linkers.
Combinations of cleavable linkers can also be used to allow sequential cleaving from a single bead.
Less common, but no less useful, are selectively cleavable linkers.
Any of the cleavable linkers described therein may be used with the present invention.
Some linkers can be cleaved by peptidases, i.e. peptidase cleavable linkers.
Any cleavable linkers used in the target probes can be used in the control probes.
Some linkers can be cleaved by esterases, i.e. esterase cleavable linkers.
Preferred cleavable linkers in this application cleave within the ion source of the mass spectrometer.
Fig . 2 shows some functional molecules, which include some cleavable linkers.
Preferred cleavable linkers are photo-cleavable.
Another class of suitable spacer-moieties comprises cleavable spacer-moieties, or cleavable linkers.
Cleavable linkers are, in many embodiments of the invention preferred.
Fig . 3 shows some functional molecules useful in the invention, including some cleavable linkers.
Preferred cleavable linkers appear to be chemically or photo-cleavable.
Fig . 2 shows some functional molecules useful in the invention, which include some cleavable linkers.
Example, more cleavable linkers with ester bonds instrumentation.
Figure 34 Chemical Structures of examples for cleavable linkers.
Preferred cleavable linkers include photolabile linkers and TFA-labile linkers.
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Examples of using Linkers
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Often linkers provide support for overlays
A variety of cleavable linkers are known in the art
The linkers between these domains are flexible
Examples of using Cleavable
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Other cleavable linkers require hydrogenolysis or photolysis
Suitable proteolytically cleavable linkers are described above
Such cleavable fluorogenic substrates are commercially available
