Examples of 'clostridial neurotoxin' in a sentence
Meaning of "clostridial neurotoxin"
clostridial neurotoxin: Clostridial neurotoxin refers to a type of toxin produced by certain species of Clostridium bacteria that can affect the nervous system and cause serious health issues
How to use "clostridial neurotoxin" in a sentence
Basic
Advanced
clostridial neurotoxin
In one embodiment the clostridial neurotoxin may be a TeNT.
The clostridial neurotoxin that is the subject of said use.
This compound can be produced by modifying a clostridial neurotoxin or fragment thereof.
Clostridial neurotoxin for use in the treatment of nasal congestion.
Therefore in one embodiment there is provided a clostridial neurotoxin comprised in an elution buffer.
Suitably the clostridial neurotoxin may be a substantially pure clostridial neurotoxin.
The present invention comprises contacting a cation exchange resin with a composition comprising a clostridial neurotoxin.
Suitably the clostridial neurotoxin may be in a substantially pure state.
The translocation domain is the HN domain of a clostridial neurotoxin.
Concentration of clostridial neurotoxin present in a fraction eluted from a cation exchange resin.
Wherein the polypeptide lacks a functional Hc domain of a clostridial neurotoxin.
The Clostridial neurotoxin can be a hybrid neurotoxin.
In another embodiment a composition comprising a clostridial neurotoxin may be admixed with a cation exchange resin.
A Clostridial neurotoxin comprises a polypeptide having three amino acid sequence regions.
The polypeptides of the present invention lack a functional HC domain of a clostridial neurotoxin.
See also
The Clostridial neurotoxin is administered in a therapeutically effective amount to alleviate a symptom of a stretch mark.
The polypeptides of the present invention lack a functional HC domain of a clostridial neurotoxin as claimed.
The Clostridial neurotoxin is administered in a therapeutically effective amount to alleviate a symptom of a skin disorder.
A method for purifying a clostridial neurotoxin comprising,.
Thus, clostridial neurotoxin fragments do not offer solutions to the problems identified.
Recovering the single-chain clostridial neurotoxin.
Concentration of clostridial neurotoxin in a starting composition with the amount e . g.
A pharmaceutical composition comprising the recombinant clostridial neurotoxin of any one of claims 1 to 6.
Separating the clostridial neurotoxin from the cation exchange resin ; and.
With the proviso that the polypeptide is not a clostridial neurotoxin ( holotoxin ) molecule.
Concentration of clostridial neurotoxin obtained after carrying out a method and / or use of the invention.
A method according to claim 1, wherein the separated clostridial neurotoxin is in a substantially pure state.
In one embodiment, the translocation domain is a HN domain ( or a fragment thereof ) of a clostridial neurotoxin.
In one example a clostridial neurotoxin may be obtainable e . g.
And with the proviso that the polypeptide is not a naturally-occurring clostridial neurotoxin molecule ;.
Described herein is a clostridial neurotoxin obtainable e . g.
A polypeptide according to any preceding claim, wherein the translocation domain comprises a clostridial neurotoxin translocation domain.
An analgesic Clostridial neurotoxin derivative comprising,.
Preferably, the neurotoxin used is a Clostridial neurotoxin.
A composition comprising a Clostridial neurotoxin derivative, said composition comprising,.
The method of claim 15, wherein the translocation domain comprises a clostridial neurotoxin translocation domain.
The kit also comprises a Clostridial neurotoxin composition, such as a botulinum toxin composition.
The translocation component of the present invention is preferably a clostridial neurotoxin H-chain or a fragment thereof.
A composition comprising a Clostridial neurotoxin derivative, said Clostridial neurotoxin derivative comprising a polypeptide including,.
A second endopeptidase domain derived from a Clostridial neurotoxin BoNT / E subtype ;.
Alternately, the administered Clostridial neurotoxin may have a direct effect upon the stretch mark.
In one embodiment, the polypeptides lack the last 50 C-terminal amino acids of a clostridial neurotoxin holotoxin.
In another embodiment, a chimeric clostridial neurotoxin may contain a portion e . g.
A polypeptide according to any of Claims 7-9, wherein the translocation domain comprises a clostridial neurotoxin translocation domain.
Alternately, the administered Clostridial neurotoxin may have a direct effect upon the skin disorder.
A first endopeptidase domain derived from a Clostridial neurotoxin BoNT / A subtype, and.
The substrate specificities of the various clostridial neurotoxin light chains other than BoNT / A are known.
Polypeptides lacking the last 50 C-terminal amino acids of a clostridial neurotoxin holotoxin are described herein.
The use of claim 13, wherein the Clostridial neurotoxin is used without conjugation to another drug.
The " translocation element " comprises a portion of a clostridial neurotoxin H chain having a translocation activity.
You'll also be interested in:
Examples of using Neurotoxin
Show more
The neurotoxin has compromised your judgment
This venom contains a neurotoxin called mandaratoxin
When attacked puffer fish release a neurotoxin
Examples of using Clostridial
Show more
The clostridial species often require cultivation
It looks like some sort of clostridial organism
Clostridial infections also occur at this age
