Examples of 'codon optimization' in a sentence
Meaning of "codon optimization"
codon optimization: The process of selecting the most efficient codons (a sequence of three nucleotides that form a unit of genetic code in DNA or RNA) for encoding a specific protein. This is done to improve the efficiency and accuracy of protein expression in genetic engineering
How to use "codon optimization" in a sentence
Basic
Advanced
codon optimization
Commercial codon optimization programs are also available.
This sequence was synthesized de novo after codon optimization.
Codon optimization has a number of other advantages.
Any suitable method of codon optimization may be used.
Codon optimization may not be required.
A varietyof techniques for codon optimization are known in the art.
Codon optimization includes use of more preferred codons.
These substitutions were alone or in combination with human codon optimization.
A variety of codon optimization schema are known in the art.
There are several methods and software tools known in the art for codon optimization.
Certain codon optimization techniques are known in the art.
A non-limiting example of a type of gene optimization is codon optimization.
Methods for codon optimization are known in the art.
If desired, expression in a particular host can be enhanced through codon optimization.
Techniques for codon optimization are known in the art.
See also
Therefore, the hairpin structures were eliminated during the codon optimization process.
Codon optimization programs are available as freeware or from commercial sources.
The invention also embraces codon optimization to suit optimal codon usage of a host cell.
Codon optimization may be based on highly expressed mammalian genes.
In some instances, codon optimization can be preferable.
Codon optimization may be used to increase the expression level of the protein.
However, any other suitable methods of codon optimization may be used.
The use of codon optimization is known to those skilled in the art.
To create this coding sequence, one utilizes a liver-directed codon optimization strategy.
Techniques for codon optimization in different hosts are well known in the art.
Expression optimization can also be achieved, including, for example, expression cassette orientation and codon optimization.
Tools for codon optimization for expression in a heterologous host are readily available.
Testing the anti-EGFR1 Fab coding sequences with different codon optimization pattern.
Codon optimization techniques are well within the skill of those in the art.
Two such techniques include codon optimization and gene mutation, as described below.
Codon optimization does not alter the amino acid sequence of the encoded protein.
To increase heterologous l1 protein levels, a codon optimization strategy was used for production under bioreactor conditions.
Codon optimization is a generic technique to achieve optimal expression of a foreign gene in a cell system.
Further details of the codon optimization process are provided in Example 8.
Codon optimization and gene synthesis is performed by GeneArt Gmbh.
Additional information for codon optimization is available, e . g.
Single codon optimization offers a good starting point for improving expression levels of proteins of interest.
Repeat steps ( 1 ) and ( 2 ) for different codons until achieving the desired level of codon optimization.
This allows for codon optimization that may result in higher expression levels.
Codon optimization of the parvoviral Rep protein is discussed in more detail hereafter.
The UGT1A1 underwent codon optimization according to several different algorithms.
Codon optimization can be performed as follows,.
Additional information for codon optimization is available, e.g., at the codon usage database of Genbank.
Thus codon optimization of the gene encoding XTEN sequences can be very desirable.
Simultaneously, codon optimization may be performed to provide for potentially optimal expression.
Further, codon optimization of silent mutations may be utilized for improvement of protein expression.
Codon optimization may render gag-pol expression Rev independent.
Also codon optimization of human factor VIII cDNAs leads to high-level expression.
Codon optimization was based on Table 1 for Prototheca sp.
Codon optimization and AAV vector construct,.
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Examples of using Codon
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Each codon corresponds to one amino acid
Nonsense mutations code for a stop codon
Codon means a basic unit of genetic code
Examples of using Optimization
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As a tool for optimization of the supply chain
Optimization and standardization of nucleic acid extractions
Active routes for the optimization of resources