Examples of 'codon optimized' in a sentence

Meaning of "codon optimized"

codon optimized: This phrase is commonly used in genetics and biotechnology to refer to the process of modifying genetic sequences in a way that enhances translation efficiency and protein expression

How to use "codon optimized" in a sentence

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codon optimized
Codon optimized sequences can be chemically synthesized.
Cells comprising codon optimized lentiviral particles.
The nucleic acid sequences shown have been codon optimized.
The nucleic acid is codon optimized for expression in a tomato plant.
The transgene encoding the tumor may be a codon optimized transgene.
The genes can be codon optimized for expression in a target host cell.
Only codons relating to INS may be codon optimized.
Thus constructs containing codon optimized sequences have been prepared and tested.
The DNA sequences are unique as they are codon optimized.
The nucleic acid may have been codon optimized for expression in bacteria.
The KOD codon optimized sequence contains a PvuII restriction site and an EcoRI restriction site.
The nucleotide sequence was codon optimized for expression in CHO cells.
This consensus DNA vaccine was also RNA optimized and codon optimized.
Such nucleic acids have been codon optimized to improve protein expression levels.
The codon optimized nptII cassette was also based on this Genbank Accession number.

See also

The designed constructs were codon optimized for expression in Escherichia coli.
A site-directed polypeptide can be codon optimized.
The transformants with the codon optimized cassette grew on the sucrose containing plates.
Thus, the nucleotide sequences canreadily be codon optimized.
The sequence was codon optimized for the expression of the encoded polypeptide in mammalian cells.
The invention further comprehends the Cas protein being codon optimized for expression in aEukaryotic cell.
Subsequently the codon optimized sequence of DcUGT2 was cloned and expressed in yeast.
In one further embodiment, said nucleic acid is codon optimized.
A coding sequence used may be codon optimized for the specific host used for expression.
Thus, the nucleotide sequences can readily be codon optimized.
Protein and Codon optimized nucleotide sequences.
In one embodiment, coding region of the nucleic acid sequence is codon optimized.
Also shown are the codon optimized sequences for the full VJ and VDJ regions.
Thus, the nucleotide sequences of the invention can readily be codon optimized.
In one embodiment, the expression library is codon optimized for expression in mammalian cells.
Codon optimized nucleic acid sequence coding for the a-chain of human FSH.
In some embodiments, the nucleotide sequence is codon optimized for bacterial expression.
The strategy for codon optimized gag-pol sequences may be used in relation to any retrovirus.
In one embodiment, the expression library is codon optimized for expression in yeast.
Sequences of the codon optimized genes and encoded polypeptides are provided in section “ SEQUENCES ”.
In one aspect, the nucleic acid has been codon optimized for expression in bacteria.
RtGFP is a codon optimized GFP gene optimized for GC-rich genome.
In some embodiments, the nucleic acid has been codon optimized for expression in bacteria.
For example the codon optimized sequence of horse granzyme B is shown as SEQ ID NO, 9.
Advantageously, the nucleotide sequence encoding the SaCas9 is codon optimized for expression in a eukaryotic cell.
A Leishmania codon optimized version of the mature IGF-II is shown in Figure 2 Langford et al.
In one embodiment, the CD polynucleotide comprises a human codon optimized sequence.
All sequences were then codon optimized for human expression by GeneArt ( Germany ).
Therefore, the respective genes or variants thereof may be codon optimized for E. coli expression.
Applicants have generated codon optimized Cas9 orthologs to advance expression in eukaryotic cells.
In this process, both the VH and VI regions of these antibodies were codon optimized.
The hfB3 nucleic acid coding sequence was codon optimized for optimal expression in mammalian cells.
These codon optimized sequences are identified as version 3 ( v3 ) throughout the specification.
In one embodiment, the expression library is codon optimized for expression in E. coli.
Example 3, Cloning of codon optimized KOD and Pfu polymerase I sequences into expression vector pKBexp.

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Each codon corresponds to one amino acid
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Codon means a basic unit of genetic code
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