Examples of 'complement factor' in a sentence
Meaning of "complement factor"
complement factor - Denotes a component or element that enhances or completes something, often used in a technical or scientific context
How to use "complement factor" in a sentence
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complement factor
Targeting complement factor h for treatment of diseases.
In principle antibodies against any complement factor may be of use.
Complement factor abnormal.
Methods for industrial scale production of therapeutic complement factor h preparations from human plasma.
Complement Factor H was eluted from the resin utilizing a solution containing approx.
Some embodiments of the invention use a complement factor B analog for attenuating complement activity.
Complement factor H and MCP act in conjunction to control the complement activation in host cells.
This may be advantageous for the downstream purification of the complement factor B protein analog.
An intron can be from a complement factor B gene or a heterologous intron.
The Fc region further comprises a region that binds to complement factor C1q protein.
The invention extends to complement Factor H preparations obtained by any of the above mentioned processes.
Compositions and methods for modulating complement factor B expression.
Human complement factor H has been determined to be a marker for urinary bladder carcinomas R.
There is no diagnostic test for complement factor H deficiency.
Targeting complement factor h for treatment of diseases by the use of cr2-fh molecules.
See also
The invention also provides various complement factor B analogs.
More subtle changes in Complement Factor H have recently also been linked with human disease.
Has diminished protease activity as compared to the corresponding native complement factor B protein ;.
Described herein are examples of complement factor B protein analogs of the invention.
The complement factor B analog comprises a substitution of a free cysteine amino acid ;.
The present invention provides pharmaceutical complement Factor H preparations produced by the methods of the invention.
Complement factor C3 deposition is commonly associated with immunoglobulin deposits on basement membranes in the kidney.
For inhibiting the binding of Complement Factor H to either ligands or tissues.
Demonstration of ability of 6F6 to interfere with amyloid beta binding to complement factor I.
There is no complement factor H deficiency.
Zimura is designed to target and inhibit complement factor C5.
Or she 's got complement factor h deficiency.
A method according to claim 1 to 6 wherein the fraction comprising complement Factor H is a waste fraction.
This gene encodes complement factor B, a component of the alternative pathway of complement activation.
The first polypeptide is the A subunit of human complement factor C1q, as described above.
In some embodiments, a complement factor B analog comprises a mutation of a free cysteine amino acid.
Viral Vectors The present invention includes viral vectors encoding a complement factor B analog ( s ) of the invention.
Further purifying complement Factor H by at least one purification method selected from the group,.
The first polypeptide is the A subunit of human complement factor C1q.
Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay.
Complement factor H polymorphism and age-related macular degeneration.
Autoantibody positive, complement factor abnormal.
IgG and complement factor C3 accumulation in injured endothelial cells and nonendothelialized intima has been observed.
Piperidinyl-indole derivatives complement factor B inhibitors and uses thereof.
The present invention is directed to a kit for assaying a test sample for Complement Factor H ( CFH ).
A method for purification of complement Factor H in a solution comprising the steps of,.
It has been shown that gC1q-R could bind the globular head of complement factor 1.
Wherein the purification of complement Factor H comprises the following process steps,.
Inter Alia the following in vitro tests may be used Human complement factor D assay, Method 1.
In some embodiments, a complement factor B analog comprises mutations of amino acids that interact with DAF.
Asherson et al ., described two sibling with hereditary complement factor 2 deficiencies.
Rare, Complement factor abnormal.
For exemplary purposes, specific analogs of complement factor B protein are described herein.
Complement factor H ( FH ) is a single polypeptide chain plasma glycoprotein.
Polyethylene glycol ( PEG ) can be attached to a complement factor B protein analog of the invention.
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