Examples of 'complement inhibitor' in a sentence
Meaning of "complement inhibitor"
complement inhibitor: A substance or agent that blocks or restricts the activity of complement proteins in the immune system
How to use "complement inhibitor" in a sentence
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complement inhibitor
A complement inhibitor may be a protein or protein fragment.
An immunomodulator can be a complement inhibitor or an immunosuppressant.
The complement inhibitor may inhibit the activation of complement.
A first component is a complement inhibitor.
The complement inhibitor polypeptide may also be fused to a marker domain.
Eculizumab is a humanized monoclonal antibody that acts as a terminal complement inhibitor.
The complement inhibitor polypeptide of the invention is derived from a tick.
An immunomodulator according to the present invention can be a complement inhibitor or an immunosuppressant.
Complement inhibitor molecules described herein may be derived from a haematophagous arthropod.
Also described herein is that a complement inhibitor may be a protein or protein fragment.
In specific embodiments, the immunomodulator is a complement inhibitor.
In some embodiments, a complement inhibitor may be a protein or protein fragment.
Acquired complement deficiency due to receipt of the terminal complement inhibitor eculizumab Soliris.
In certain embodiments, a complement inhibitor may be a protein or protein fragment.
In an alternate embodiment, the immunomodulator is a complement inhibitor.
See also
In some embodiments, the complement inhibitor inhibits the activation of complement.
In some embodiments, the complement regulator may be a complement inhibitor.
Preferably, the complement inhibitor will inhibit both the classical and alternative pathways of complement activation.
Acidified serum in the absence of added complement inhibitor produces maximum lysis.
The active agent comprises an anti-inflammatory agent and the anti-inflammatory agent is a complement inhibitor.
Preferably, the complement inhibitor polypeptide is derived from the tick Ornithodoros moubata.
A preparation according to claim 1 or 2 wherein the polypeptide has complement inhibitor activity.
The complement inhibitor inhibits post-ischemic myocardial inflammation and necrosis Weisman et al.
The CR2-FH molecule may be a more potent complement inhibitor than the naturally occurring FH protein.
The complement inhibitor for use according to claim 1, wherein the subject,.
Overall, Crry-Ig is potent complement inhibitor.
The at least one complement inhibitor is selected from a group consisting of CD46 or DAF ;.
The second therapeutic agent may, but need not be, a complement inhibitor.
For example, an antibody complement inhibitor may include an anti-C5 antibody.
The X-axis represents the concentration of a given complement inhibitor ( µM ).
The complement inhibitor is CD46, optionally wherein the promoter is CAG.
The method according to item 7, wherein the complement inhibitor is a single-domain antibody.
Preferably, the complement inhibitor polypeptide of the invention inhibit cleavage of C5 by direct binding to C5.
Group 4 serves as a control ( no complement inhibitor therapy ).
As described herein, the complement inhibitor polypeptide inhibits cleavage of C5 by a C5 convertase.
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