Examples of 'conformational epitope' in a sentence
Meaning of "conformational epitope"
conformational epitope: a term used in immunology to describe the specific shape or structure on an antigen that binds to an antibody
How to use "conformational epitope" in a sentence
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conformational epitope
Optionally the antibody binds a conformational epitope.
This indicates a conformational epitope for these antibodies.
Monoclonal antibodies specific for a discontinuous conformational epitope.
Conformational epitope 스크리닝.
Typically the epitope is a conformational epitope.
Typically a conformational epitope comprises an increased number of amino acids relative to a linear epitope.
Determining whether an antibody recognises a conformational epitope is also straightforward.
Typically a conformational epitope encompasses an increased number of amino acids relative to a linear epitope.
Preferably the sugar addition site is near a conformational epitope.
A conformational epitope is composed of discontinuous sections of the antigen 's amino acid sequence.
The length of the antigen is sufficient to maintain an immunoreactive conformational epitope.
The peptide mimotopes essentially convert a conformational epitope made from a complete protein into a small peptide.
In the present disclosure the antibody molecule binds a conformational epitope.
However, the conformational epitope does not fall within the claimed invention.
These cysteine residues coordinate zinc and thereby represent a conformational epitope.
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In contrast, conformational epitope consists of amino acids that are not arranged sequentially.
This could mean that these immunoglobulin preparations recognize a conformational epitope.
For example, a conformational epitope comprises amino acid residues which require an element of structural constraint.
These cystein residues coordinate zinc and thereby represent a conformational epitope.
An antibody that recognizes the conformational epitope may only bind under mild, non-denaturing procedures.
Preferably, the recognised epitope is a conformational epitope.
For example, the conformational epitope is dependent on disulphide bond formation within Fnl4.
The determinant or epitope may represent a peptide fragment or a conformational epitope shared by said members.
A conformational epitope is dependent on the 3-dimensional structure.
The VHH antibody binds to an intracellular conformational epitope of the receptor.
This conformational epitope has been defined by monoclonal antibody H 11.
The above described VHH antibody binds a conformational epitope of the receptor.
A conformational epitope of NS3/4a was obtained as follows.
A peptide which mimicks at least part of the conformational epitope of an antibody molecule PBS.
In a particular embodiment the determinant is an epitope, and more particularly a conformational epitope.
The Herceptin antibody binds to a conformational epitope in the ECD domain.
In one embodiment, the anti-GITR antibodies described herein bind to a conformational epitope.
These results demonstrate a conformational epitope for Antibody 1.
Preferred binding moieties are antiC5a antibodies that bind to this conformational epitope.
Of course, a format that denatures the HCV conformational epitope should be avoided or adapted.
Thus, the minimal epitope is most likely part of a discontinuous epitope or a conformational epitope.
Of course, a format that denatures the HCBI conformational epitope should be avoided or adapted.
If multiple non-contiguous peptides are bound by the protein, the protein may bind a conformational epitope.
More preferably, the epitope is a conformational epitope of human tau.
Advantageously, said antibody is a conformational antibody, i.e. an antibody recognizing a conformational epitope.
Of course, a format that denatures the PMC virus conformational epitope should be avoided or adapted.
In other embodiments, the polypeptide comprises a conformational epitope.
Binding region 1 indentifies a Cluster A conformational epitope that is distal to the lectin / ligand binding domain.
An epitope can be a linear, sequential epitope or a conformational epitope.
Another MAb 5G7 which recognizes conformational epitope on BACE1 were used as positive control.
In other aspects, the epitope of the binding construct is a conformational epitope.
Another MAb 5G7 that recognizes conformational epitope on BACE1 were used as positive control . FIG.
Figure 4 provides evidence indicating that the epitope on HSA for FcRn is a conformational epitope.
The epitope recognized by the mAb1379 is a conformational epitope that is not a linear epitope.
In a specific embodiment of this invention, a human papillomavirus L1 protein comprises a heterologous conformational epitope from HPV 6.
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Examples of using Conformational
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She is interested in conformational change during catalysis
Conformational preferences of diastereomeric rotamers have been investigated
An example of a pathogenic conformational disease protein is PrPSc
Examples of using Epitope
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Typically an epitope has specific charge characteristics
A cryptotope can also be referred to as a cryptic epitope
Identification of this epitope is a matter of routine experimentation
