Examples of 'conformational epitopes' in a sentence

Meaning of "conformational epitopes"

conformational epitopes - specific areas on molecules that antibodies bind to during an immune response

How to use "conformational epitopes" in a sentence

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conformational epitopes
Epitopes can be either linear or conformational epitopes.
A range of conformational epitopes for the pentameric complex are known.
Antibodies can bind linear or conformational epitopes.
Such conformational epitopes are distributed on the extracellular side of the plasma membrane.
Most antibodies recognize conformational epitopes.
Methods to reproduce conformational epitopes from MHC determinants are known in the prior art.
Such antibodies are particularly useful in the case of conformational epitopes.
Antibodies with linear or conformational epitopes are within the invention.
Some epitopes are linear epitopes while others are conformational epitopes.
Two of these antibodies recognize conformational epitopes and the other two lineal epitopes.
A similar change in epitope recognition is likely for conformational epitopes.
This may affect the structure of important conformational epitopes and result in inefficient immune responses.
Neutralizing activity in this study appears to be largely dependent upon conformational epitopes.
This arrangement is typical of conformational epitopes for antibody binding.
Fragmentation of a protein or reduction of its disulfide bonds often destroys conformational epitopes.

See also

We previously demonstrated that conformational epitopes to HPV can be mapped.
A comparison of the results will indicate whether the antibodies bind conformational epitopes.
Virus-like particles exhibit conformational epitopes exhibited by native viruses of similar sequence.
It also suggests that the purified protein retains at least some conformational epitopes.
The modified NS3 polypeptides retain conformational epitopes and hence immunoreactivity, while eliminating protease activity.
The two antibodies of this third group are qualified as recognizing discontinuous scattered conformational epitopes.
Other peptides bearing either linear or conformational epitopes are known in the art.
In fact, a coating with EBs would allow the detection of antibodies raised against conformational epitopes.
Epitopes can be linear sequence epitopes or conformational epitopes ( conserved binding regions ).
Conformational epitopes have been described in PCT Publ . No.
The RSV epitopes can be linear epitopes or conformational epitopes.
Conformational epitopes present in the NS3/4a region are readily identified using methods discussed above.
In this manner, amino acid contributions to conformational epitopes were considered.
Conformational epitopes present in, e.g., the NS3/4a region are readily identified using methods discussed above.
The non-reactors are probably directed against the conformational epitopes.
Conformational epitopes preferably comprise between 8 and 20 discontinuous amino acids, preferably between 8 and 15 amino acids.
The antigens according to the invention include linear and / or conformational epitopes.
Specifically, the antibodies as described herein bind conformational epitopes of a BLyS monomeric protein.
Smaller fragments have been identified as antigenic regions, for example, in conformational epitopes.
In specific embodiments, the antibodies of the invention bind conformational epitopes of a BLyS monomeric protein.
These results demonstrate that the prototype L1 protein does not present conformational epitopes.
These monoclonal antibodies are directed against conformational epitopes located in the HIV gp120.
In general, B cell epitopes of antigens are longer, and are known as conformational epitopes.
Nevertheless, some studies have been performed to identify conformational epitopes E.
The data show that the prototype HPV16 strain lacks conformational epitopes.

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Examples of using Epitopes
At least four IgE epitopes have been identified
Epitopes of GnRH are also captured by the definition
Cancer vaccines containing epitopes of oncofetal antigen
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Examples of using Conformational
She is interested in conformational change during catalysis
Conformational preferences of diastereomeric rotamers have been investigated
An example of a pathogenic conformational disease protein is PrPSc
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