Examples of 'costimulatory' in a sentence
Meaning of "costimulatory"
costimulatory (adjective): Describing something that enhances or facilitates a specific action, process, or function through joint stimulation or interaction
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- Of or pertaining to co-stimulation.
How to use "costimulatory" in a sentence
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costimulatory
Costimulatory factors are well known in the art.
The interaction properties of costimulatory molecules revisited.
Costimulatory pathways play an important role in tumor development.
It is involved in cellular adhesion and costimulatory signaling.
The addition of costimulatory cells does not reverse unresponsiveness.
These compounds may exert a costimulatory effect.
Costimulatory molecules thus gain attention as potential therapeutic targets.
This secondary signal is called costimulatory signal.
The costimulatory signaling domain is derived from a costimulatory molecule.
No significant expression of positive costimulatory molecules was detected.
Costimulatory molecule surface expression following infection with recombinant viruses.
This molecule has a costimulatory function.
Modulation of a costimulatory signal results in modulation of effector function of an immune cell.
Some of these adhesion molecules provide costimulatory signals.
The effect of the triad of costimulatory molecules on DCs was completely unexpected.
See also
Immunoaffinity chromatography also can be used to purify costimulatory polypeptides.
Methods for assessing such costimulatory agents are well known in the literature.
These results corroborate autocostimulation as an operant mechanism of delivering costimulatory signals.
It is derived from a costimulatory molecule.
A similar costimulatory immune system pathway is being analyzed for this type of application.
The extracellular portion of such costimulatory molecules can also be used.
Genomic structure of recombinant fowlpox viruses expressing murine or human costimulatory molecules.
The second signal is transmitted by costimulatory molecules on the surface of the dendritic cell.
A costimulatory intracellular signaling domain can be derived from the intracellular portion of a costimulatory molecule.
Inhibitory receptors that bind to costimulatory molecules have also been identified on immune cells.
The vector vaccine comprises foreign nucleic acid sequences encoding three costimulatory molecules.
Modulation of costimulatory molecules and their receptors permits the modulation of various immune functions.
These previous studies were carried out using two costimulatory molecules and retroviral vectors.
However, a second costimulatory signal is necessary to achieve complete activation.
Such methods can be used to identify interactions between costimulatory ligands and costimulatory receptors.
T cell costimulatory pathways, promising novel targets for immunosuppression and tolerance induction.
Adjuvants can be administered in conjunction with costimulatory molecules to additionally augment the immune response.
Intracellular signaling domains can include primary intracellular signaling domains and costimulatory signaling domains.
The foreign genes encoding the costimulatory molecules may be obtained from a variety of sources.
The present invention provides plasmid vectors comprising a foreign nucleic acid sequence encoding three costimulatory molecules.
Represents a family of costimulatory molecules which are members of the Ig gene superfamily.
Other CAR described herein contain a second costimulatory domain.
This molecule can receive a costimulatory signal delivered by a ligand on B cells or other APCs.
The encoded CAR molecule may further comprise a sequence encoding a costimulatory domain.
Newer approaches incorporating costimulatory molecules that enhance Tcell activation are also being investigated.
The fate of a T cell recognizing antigenic peptide is entirely determined by the costimulatory signal.
Human monoclonal antibody against a costimulatory signal transduction molecule AILIM and pharmaceutical use thereof.
These include inter alia its property of reducing the expression of costimulatory molecules on DC.
Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes.
The peptide of the invention is an immunomodulatory peptide capable of modulating a T cell costimulatory pathway.
CsA blocked this costimulatory effect.
Preferably, the soluble compositions comprise an extracellular domain of a costimulatory molecule.
Bromelain can increase costimulatory signals to T cells vía an action on B cells.
Methods and compositions for the inhibition of modulation of T cell costimulatory pathway by a pathogenic agent.
Constitutive expression of a costimulatory ligand on antigen-presenting cells in the nervous system drives demyelinating disease.
