Examples of 'cyclin' in a sentence
Meaning of "cyclin"
cyclin (noun): A family of proteins involved in regulating the cell cycle and promoting cell division. Cyclins work in conjunction with cyclin-dependent kinases (CDKs) to control the progression of cells through different stages of the cell cycle
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- Any of a group of proteins whose presence in a cell varies through its cycle, and that regulates this cycle by forming a complex with kinase
How to use "cyclin" in a sentence
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cyclin
Inhibitors of cyclin inhibitors can also be detected.
Cancer could be caused by the hyperfunction of a type of cyclin.
Cyclin dependent kinases pair up with cyclins to become operational.
My sister is a paralympic gold medalist in cyclin.
Abnormal cyclin levels result in too few or too many divisions.
The discovery of the first cyclin.
Cyclin dependent kinases.
The area is popular for cyclin.
Cyclin dependent kinase.
The progression of interphase is the result of the increased amount of cyclin.
In certain preferred embodiments the analytes are cyclin dependent kinase inhibitors.
A protein kinase that is catalytically active only when bound to a cyclin.
Proteins with no homology to the cyclin family can be direct activators of CDKs.
Cyclin is the special protein within a cell that regulates the cell cycle.
The control of each checkpoint is controlled by cyclin and cyclin dependent kinases.
See also
The amount of cyclin rises and falls with each stage of the cycle.
Numerous recent studies have thus focused on cyclin and cdk involvement in cancer.
Cyclin dependent kinases play a key role in regulating the cell cycle machinery.
These data suggest that the defect in cyclin proteolysis is due to defective ubiquitination.
Transformation of the cell will result in selective rearrangement of subunits in the cyclin complexes.
MyoD is inhibited by cyclin dependent kinases CDKs.
The activity of these molecules is controlled by phosphorylation events and by association with cyclin.
No CLN type cyclin has yet been described in mammalian cells.
In the eukaryotic cell cycle a key role is played by the cyclin dependent kinases.
The APC complex is a cyclin degradation system that governs exit from mitosis.
Additional agents can induce the expression of an inhibitor of the cyclin inhibitor protein.
We are currently testing cyclin D and its cognate kinases for a role in this progression.
The second process is the highly regulated synthesis and degradation of the cyclin proteins.
Subsequently the cells in the sample containing cyclin E can be detected using a microscope.
The CDK is only active when bound to a cyclin.
Black bars indicate the percent of patients where cyclin B was expressed in neuronal nuclei.
CDKs are catalytically active only when bound to a regulatory cyclin.
Securin and cyclin B are also stabilized before the anaphase transition by the unattached kinetochores.
There is considerable specificity in which cyclin binds with CDK.
High levels of cyclin E can cause unrestrained cell division and are associated with poorer survival.
CDKs require for activation the association with a regulatory cyclin subunit.
Protein cyclin A governs this process by keeping the process going until the errors are eliminated.
An active CDK is composed of a catalytic subunit and a regulatory subunit called cyclin.
CDK complexes are formed via the association of a regulatory cyclin subunit and a catalytic kinase subunit.
Cyclin B plays in integral role in many types of cancer.
In this procedure the sample is incubated with antibodies against cyclin E which can be coloured.
Cyclin B is a member of the cyclin family.
Control of sleep by cyclin A and its regulator.
Cells were transfected with dsRNAs corresponding to either cyclin E or lacZ.
The protein cyclin E is expressed in a cell cycle specific manner.
Extracts were prepared from cells transfected with cyclin E dsRNA.
The cyclin pleased by Zhdanov.
The most studied homologues of cyclin D are found in yeast and viruses.
CDKs are composed of a catalytic CDK subunit and a regulatory cyclin subunit.
Transcription of cyclin A is tightly regulated and synchronized with cell cycle progression.
