Examples of 'deaminase' in a sentence
Meaning of "deaminase"
deaminase is an enzyme that catalyzes the removal of an amino group from a molecule, often as part of metabolic processes in living organisms. Deaminases play a crucial role in nitrogen metabolism and the biosynthesis of various molecules, including proteins and nucleic acids. These enzymes are essential for maintaining cellular function and homeostasis
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- An enzyme that catalyses deamination
How to use "deaminase" in a sentence
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deaminase
Deaminase activity of both fusión proteins were examined.
It is characterized by a deficiency of the enzyme porphobilinogen deaminase.
Inhibition of deaminase increased intracellular araA.
This enzyme is also called ethanolamine deaminase.
Bovine liver adenosine deaminase can be used as standards.
The deaminase may be a cytidine deaminase or a deoxycytidine deaminase.
A deficiency is associated with myoadenylate deaminase deficiency.
Adenosine deaminase is known to exist predominantly in lymphocytic cells.
Stable recombinant adenosine deaminase enzymes are provided herein.
It is only a moderate substrate of cytidine deaminase.
Suitable enzymes include deaminases such as adenosine deaminase.
Elapegademase is a PEGylated recombinant adenosine deaminase.
Cytosine deaminase is absent in plants.
It is prone to deamination by adenosine deaminase to inosine.
Adenosine deaminase deficiency.
See also
Viramidine is a ribavirin prodrug converted ribavirin by adenosine deaminase to in hepatocytes.
Adaptive evolution of threonine deaminase in plant defense against insect herbivores.
An example of a prodrug activating gene is the cytosine deaminase gene.
Porphobilinogen deaminase is the third enzyme in the heme biosynthetic pathway.
Characterization of the deaminase activity.
Resistance to cytosine arabinoside has also been attributed to cytidine deaminase.
Other cytidine deaminase inhibitors have previously been described in international application no.
Azacitidine undergoes spontaneous hydrolysis and deamination mediated by cytidine deaminase.
Suppression or deletion of adenosine deaminase in children is associated with severe immunosuppression.
Metabolism of azacitidine is by spontaneous hydrolysis and by deamination mediated by cytidine deaminase.
The modified cytosine deaminase gene was then cloned into pLXSN.
Deoxyadenosine and renders the molecule resistant to deamination by adenosine deaminase.
The cytosine deaminase gene is found and expressed in a variety of microorganisms.
The heterologous domain can comprise a cytosine deaminase of the disclosure.
Elevated erythrocyte adenosine deaminase activity in patients with acquired immunodeficiency syndrome.
It is used to treat severe immune deficiency due to adenosine deaminase deficiency.
It is also possible that adenosine deaminase induction can be controlled in a similar manner.
Additional modifications were made to enhance the stability of the cytosine deaminase.
The structural gene for the deaminase may be obtained in a variety of ways.
The deoxyinosine comes from the enzymatic action of adenosine deaminase on deoxyadenosine.
A mutant lacking the deaminase activity was unable to convert deoxycytidine nucleotides to thymidine nucleotides.
Some mutations in the gene for adenosine deaminase cause it not to be expressed.
These cell populations was assayed for expression of the cytosine deaminase gene.
Incorporation of the cytosine deaminase gene into the genome was demonstrated in two ways.
The phenotype of cdd mutants was confirmed by the absence of cytidine deaminase activity.
The nucleotide sequence coding for porphobilinogen deaminase is preferably a synthetic nucleotide sequence.
The adenosine deaminase is optionally purified from a bovine source or is a recombinant adenosine deaminase.
The invention provides recombinant adenosine deaminase mutated for enhanced stability.
The adenosine deaminase activity was determined spectrophotometrically by direct measurement of changes in adenosine absorbance.
We have identified five alleles at the mouse guanine deaminase locus by cDNA sequencing.
The effect of known cytidine deaminase polymorphisms on azacitidine metabolism has not been formally investigated.
Optionally the methods of the invention may further utilize an inhibitor of adenosine deaminase.
In such instances the cytosine deaminase is produced only in tumor cells following viral replication.
Any modification is contemplated as long as the resulting protein exhibits adenosine deaminase activity.
Thus adenosine deaminase itself had no direct effect upon the pheromone response pathway.
