Examples of 'dihydrochloride salt' in a sentence
Meaning of "dihydrochloride salt"
dihydrochloride salt: This term denotes a salt formed by the reaction of a compound with hydrochloric acid, commonly used in pharmaceuticals as a way to increase solubility and stability
How to use "dihydrochloride salt" in a sentence
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dihydrochloride salt
The dihydrochloride salt was tested in the assays.
This was then converted to the dihydrochloride salt.
The dihydrochloride salt crystallized from acetone.
The product was crystallized as the dihydrochloride salt.
The dihydrochloride salt was formed for analysis.
Filtration gave the hydrated dihydrochloride salt.
The dihydrochloride salt was obtained as a hygroscopic white solid.
The material was isolated as the dihydrochloride salt.
The dihydrochloride salt is less soluble.
This material was converted to dihydrochloride salt in diethylether solvent.
The dihydrochloride salt is especially preferred.
It is commercially available as the dihydrochloride salt.
The dihydrochloride salt was obtained as a hygroscopic beige solid.
In an embodiment the pharmaceutically acceptable salt is a dihydrochloride salt.
The dihydrochloride salt is further upgraded by trituration with dichloromethane.
See also
Lyophilization gave the dihydrochloride salt.
The dihydrochloride salt was prepared.
This material was converted to the title dihydrochloride salt.
The product was obtained as a dihydrochloride salt containing one equivalent of water.
The bulk of the product was converted to the dihydrochloride salt.
This oil was converted to the dihydrochloride salt in methanol and evaporated.
The product was precipitated out of the solution as dihydrochloride salt.
There was thus obtained the dihydrochloride salt of the title compound.
Suitable acid addition salts of alexidine include the dihydrochloride salt.
Isolated as dihydrochloride salt.
Counterion analysis by ion chromatography is consistent with the dihydrochloride salt.
The dihydrochloride salt of the product was produced according to processes described previously.
The compound is the dihydrochloride salt.
Isolated as dihydrochloride salt which separated out from the reaction mixture.
Evaporation of solvent and trituration with ether gave the dihydrochloride salt.
A solid product is then isolated as the dihydrochloride salt using conventional separation procedures.
In a first embodiment of this aspect the pharmaceutically acceptable salt is a dihydrochloride salt.
A dihydrochloride salt is generated by bubbling HCl through a cold suspension of the quinoline in methanol.
Purification by the reverse phase chromatography option gives the dihydrochloride salt.
The yellow dihydrochloride salt was collected and washed with ethyl acetate followed by ether.
Sterile spectinomycin hydrochloride is said to exist in the form of the pentahydrated dihydrochloride salt.
The resulting dihydrochloride salt was obtained by filtration and washed with EtOAc and ether.
The most preferred salt of Trimetazidine for the present invention is dihydrochloride salt.
The material is upgraded by forming the dihydrochloride salt and collecting the resulting solids.
The dihydrochloride salt was collected and dried in a vacuum desiccator over KOH.
The MS and NMR were consistent with the desired product as a dihydrochloride salt.
The dihydrochloride salt was made by treatment with 2 eq.
In one embodiment, the salt is a dihydrochloride salt.
The dihydrochloride salt 8a was precipitated from acetone.
If formulated as a pharmaceutically acceptable salt, the dihydrochloride salt is preferred.
The dihydrochloride salt was prepared using the procedure described in example 8.
The product was obtained as a dihydrochloride salt and gave the following data,.
The dihydrochloride salt of the title compound was crystallized from ethanol ; m . p.
A compound as defined in any preceding claims, wherein the salt is a dihydrochloride salt.
Crystallization as the dihydrochloride salt from 2-propanol provided colorless crystals.
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