Examples of 'dose-dependent increase' in a sentence

Meaning of "dose-dependent increase"

dose-dependent increase: This term describes a situation where the effect or response to a substance or treatment varies depending on the dosage administered

How to use "dose-dependent increase" in a sentence

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dose-dependent increase
A dose-dependent increase in heart rate was also observed.
Both simulants showed a dose-dependent increase in cytotoxicity.
A dose-dependent increase of receptor activity is shown for all three receptors to both molecules.
Gleevec-induced differentiation was supported by the dose-dependent increase in hemoglobin production.
In both curves, a dose-dependent increase in the antiallodynic effect is observed.
Immunostaining for idursulfase in the brain demonstrated a dose-dependent increase in staining intensity.
Note the dose-dependent increase in the biochemical marker of differentiation.
Both of these changes showed a slight dose-dependent increase in severity and / or incidence.
Due to a dose-dependent increase in lipid peroxidation the generation of oxidative stress was assumed.
The overall incidences of all adverse events show a dose-dependent increase in the short-term studies.
Then, a dose-dependent increase in the production of cystatin C by cells exposed to corticoid was observed.
The results showed an IR dose-dependent increase in conductance.
A dose-dependent increase in luciferase activity was observed, suggesting that CPX transcriptionally activates VEGF expression.
In overdose studies conducted in cats, there was a dose-dependent increase in the QT interval.
The animals exhibited a dose-dependent increase in blood pressure as phenylephrine concentration was increased.

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Both mannosamine hydrochloride and glucosamine hydrochloride caused a dose-dependent increase in DNA levels.
The results show a dose-dependent increase in the cytotoxicity.
Dose-dependent increase in transcripts appears fully saturated at 10 nM aldosterone.
Increasing concentrations of SAG cause a dose-dependent increase in incorporation of the tritiated thymidine above baseline.
A dose-dependent increase in the synthesis or IL-8 was also observed.
Additionally, AMPK activation also promotes a dose-dependent increase in glycolysis and fatty acid oxidation in cardiomyocytes.
A dose-dependent increase in the synthesis of TNF-a was evident with escalating RR1 doses.
The treatment with r-Hu-EPO can produce a moderate and temporary dose-dependent increase on platelet reactivity.
GnRH produced a dose-dependent increase in the extracellular acidification rate of GGH3 cells.
Dose response studies of IL-6 also indicated a dose-dependent increase in the total cell numbers.
There is a dose-dependent increase in the QT interval and the corrected QT interval ( QTc ).
Figure 9B shows irradiation dose-dependent increase in km values.
There was a dose-dependent increase in survival in both treated groups following injection of product ( Table 7 ).
Figure 15 shows that irradiation caused a dose-dependent increase in glutamine-stimulated Isc.
There was a dose-dependent increase of circulating white blood cells ( WBC ), mainly lymphocytes FIG.
Quantification of neurite outgrowth showed a dose-dependent increase with the addition of sNogoR344-Fc.
A dose-dependent increase in the expression of somatostatin was observed ( Figure 3, panel e ).
Insulin also induces a rapid and dose-dependent increase in AS160 phosphorylation in skeletal muscle.
A dose-dependent increase in the expression of somatostatin was observed ( FIG . 3E ).
Stress -- particularly acute stress -- results in a dose-dependent increase in both catecholamines and cortisol.
There was a dose-dependent increase in AUC0-t and T1/2 but the difference was not statistically significant.
Thus, increased expression of NogoA causes a dose-dependent increase in AB40 levels.
There was a time - and dose-dependent increase of CALGRANULIN C secretion after stimulation with TNF alpha.
In preclinical models, GDC-0068 administration resulted in a dose-dependent increase in plasma glucose levels.
A pronounced and dose-dependent increase in brain DA metabolism was noted after sc administration of Example 11.
As shown in Figure 8, Hirulog-8 yielded a dose-dependent increase in the APTT.
Verapamil produced a dose-dependent increase in tidal volume ( VT ) and a decrease in respiration rate ( f ).
Figure 22 is a bar chart showing that activin A induces a dose-dependent increase in SOX17 + cell number.
Dexamethasone produced a dose-dependent increase in the EC50 for IL-5-mediated viability enhancement.
A dose-dependent increase in anticoagulant response to APC was observed ( Fig 4A ).
Administration of IGF-I produced a dose-dependent increase in brain ornithine decarboxylase activity ( Fig . 4 ).
FIG . 15 shows that irradiation caused a dose-dependent increase in glutamine-stimulated Isc.
Immunoglobulin IgG produced a dose-dependent increase in the spontaneous activity similar to that of? - globulin.
Addition of TPEN to the medium resulted in a dose-dependent increase in Tdfl synthesis ( Fig . 1 D ).
Addition of compound 3 caused a dose-dependent increase in inhibition of pYSTATS as illustrated in ( C ).

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