Examples of 'dose-dependent manner' in a sentence

Meaning of "dose-dependent manner"

The phrase 'dose-dependent manner' describes the relationship between the dosage or quantity of a substance/concentration and the corresponding effect or response it produces. It suggests that the effect or response increases or decreases in proportion to the dosage or concentration administered. This phrase is commonly used in scientific and medical contexts to describe how the intensity or effectiveness of a treatment or drug is influenced by varying dosages

How to use "dose-dependent manner" in a sentence

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dose-dependent manner
Cholesterol was also reduced in a dose-dependent manner.
Cell viability decreased in a dose-dependent manner as measured by quantifying calcein AM fluorescence.
Stimulate cumulus expansion in a dose-dependent manner.
The four antibodies bind in a dose-dependent manner to the insolubilized BOIIB2 antibody on plate.
Crofelemer inhibited hERG tail current in a dose-dependent manner.
This construct was activated in a dose-dependent manner by rifampicin with maximal induction at 5 µM.
All antibodies inhibited histamine release in a dose-dependent manner.
This latter effect occurred in a dose-dependent manner and within a 4 day incubation period.
They also reduce mast cell activation in a dose-dependent manner.
Compound A prevented in a dose-dependent manner the development of tolerance.
Both factors stimulate albumen synthesis in vitro in a dose-dependent manner.
HSE increased MTs in a dose-dependent manner in all groups.
The peptide demonstrated strong antimicrobial activity in a dose-dependent manner.
HDL-C concentrations increased in a dose-dependent manner following multiple dosing.
The inhibition of endothelial cell proliferation occurred in a dose-dependent manner.

See also

FP decreased the inflammatory recruiters in a dose-dependent manner for all the studied proteins Figure 2.
High-dose steroid was found to be associated with sepsis in a dose-dependent manner.
Compound A strongly inhibited CETP activity in a dose-dependent manner following both single and repeated dosing.
This swelling was markedly inhibited by treatment with ritonavir, in a dose-dependent manner.
RIF stimulated expression of procollagenase in a dose-dependent manner comparable to that induced by relaxin.
Administration of a dopaminergic agonist decreases neuron discharge frequency in dose-dependent manner.
Those were in a dose-dependent manner.
Dopamine increases the motility of the isolated hindgut in a dose-dependent manner.
LPA stimulated fibroblast proliferation in a dose-dependent manner with a maximal increase at 10 µM LPA.
Both agents significantly reduced ethanol-induced damage in a dose-dependent manner.
Kalonji killed off the bacteria in a dose-dependent manner in over half of the samples ( 12 ).
A study in pigs showed that it decreased fat growth in a dose-dependent manner.
Fig 16 shows that MTS improved in a dose-dependent manner when increasing concentration of HPGF from 3 to 20 %.
These therapies have shown that autophagy increases in a dose-dependent manner.
Oligomenorrhea and amenorrhea occur in a dose-dependent manner in most patients.
Glutamine supplementation reduces markers of intestinal permeability during running in the heat in a dose-dependent manner.
If it is used in a dose-dependent manner.
Compounds of the invention are expected to induce c-kit degradation in a dose-dependent manner.
The liver increased in weight in a dose-dependent manner with ( inip ) b b F K-NH2.
The therapy inhibited this post-translational modification in a dose-dependent manner.
This inhibition is in a dose-dependent manner.
Addition of increasing concentrations of lycopene inhibited copper ion-induced LDL oxidation moderately, in a dose-dependent manner.
The therapeutic effect may be observed in a dose-dependent manner within this range.
Liposomal-antisense oligonucleotides specific for Grb2 can inhibit the proliferation of leukemic cells in a dose-dependent manner.
Production of the 12 kD fragment can be blocked in a dose-dependent manner by tau-aggregation inhibitors.
Oxyntomodulin is capable of inhibiting pentagastrin-stimulated gastric acid secretion in a dose-dependent manner.
Potassium decreased and P and Al increased in a dose-dependent manner over the 11-day culture period.
Serotonin uptake vía the transporter was inhibited by each of them in a dose-dependent manner.
Neutrokine a modulates cell proliferation and differentiation in a dose-dependent manner in the above-described assay.
These test vectors also corrected phenotype of hypercholesterolemia in a dose-dependent manner.
VEGF could act in a similar dose-dependent manner.
Enalapril administration once daily lowered trough blood pressure in a dose-dependent manner.
Cell fluorescence increased in a dose-dependent manner FIG.
As with the cultures of mononuclear cells, TNFa is also stimulated in a dose-dependent manner.
The antibodies inhibit osteoclast differentiation in a dose-dependent manner as shown in Figure 28.

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Examples of using Dose-dependent
This results in a dose-dependent thickness reduction
Dose-dependent statistically significant suppression was observed
The capture effect is dose-dependent in compounds
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Examples of using Manner
His very manner was formed by the landscape
Manage assets to accommodate growth in an efficient manner
Sanding should be done in a manner to reduce tracking of paint
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