Examples of 'double-strand breaks' in a sentence
Meaning of "double-strand breaks"
double-strand breaks: In genetics, it refers to the breaking of both strands of the DNA double helix, which can lead to genetic mutations or chromosomal abnormalities
How to use "double-strand breaks" in a sentence
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double-strand breaks
Double-strand breaks are especially threatening to bacterial viability.
They are additionally involved in repair of double-strand breaks.
Double-strand breaks are the most dangerous damages to the cell.
Neddylation also has a role in repair of double-strand breaks.
Double-strand breaks in cellular chromatin can also stimulate cellular mechanisms of non-homologous end joining.
Radiosensitivity is determined by recognition and repair of double-strand breaks.
This causes induction of DNA double-strand breaks resulting in apoptosis.
There are two pathways for homologous recombinational repair of double-strand breaks.
ZFNs are engineered proteins that induce double-strand breaks at specific sites in an organism 's DNA.
The radiosensitivity is determined by the recognition and repair of double-strand breaks.
Double-strand breaks may also arise by DNA replication through a single-strand nick or gap.
As they suspected, the cells accumulated double-strand breaks at common fragile sites.
These microhomologies are often present in single-stranded overhangs on the ends of double-strand breaks.
Double-strand breaks can be repaired through homologous recombination or through non-homologous end joining NHEJ.
Interplay between sensing, signaling and repair of double-strand breaks in human cells.
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Abstract, DNA Double-Strand Breaks ( DSBs ) repair is essential to safeguard genome integrity.
Tell us where you would like to make double-strand breaks in the genome.
Double-strand breaks ( DSBs ) are the most deleterious DNA damages for the cells.
It has also been known to cause DNA double-strand breaks.
The NHEJ pathway for repairing double-strand breaks involves the rejoining of the broken ends.
This process is associated with repair of DNA damages, particularly double-strand breaks.
These nucleases create site-specific double-strand breaks ( DSBs ) at desired locations in the genome.
These adaptations include an extremely efficient mechanism for repairing DNA double-strand breaks.
In particular, single - and double-strand breaks in DNA can be repaired.
Dmc1 mediates homologous chromosome pairing during meiosis and repair of double-strand breaks in DNA.
Bleomycin affects DNA, producing double-strand breaks in an oxygen and metal ion-dependent process.
ATM plays a role in cell cycle delay after DNA damage, especially after double-strand breaks DSBs.
Most double-strand breaks are repaired by non-homologous end joining ( NHEJ ) or homology directed repair HDR.
CSB protein facilitates homologous recombinational repair of double-strand breaks and represses non-homologous end joining.
Telomeres are normally protected by a " cap " that prevents them from being recognized as double-strand breaks.
SIRT7 protein is required for repair of double-strand breaks by non-homologous end joining.
Ubiquitination of histone H2AX is involved in DNA damage recognition of DNA double-strand breaks.
DNA double-strand breaks ( DSBs ) are highly cell damaging.
HR is inefficient in mammalian cells but is promoted by double-strand breaks in DNA.
Of the various types of DNA damage, double-strand breaks ( DSBs ) are the most lethal.
Deinococcus radiodurans, by contrast, can survive over a thousand double-strand breaks.
By this process D. radiodurans can survive thousands of double-strand breaks per cell.
PARP-3 deficiency can lead to reduced cellular response to DNA double-strand breaks.
The single-strand annealing ( SSA ) pathway of homologous recombination repairs double-strand breaks between two repeat sequences.
In addition, CHK1 inactivation in PTEN-deficient cells leads to the accumulation of DNA double-strand breaks.
Detection, repair and signalling of DNA double-strand breaks.
CRISPR-Cas9 can target disease-causing mutation sites and introduce double-strand breaks.
The damage repaired can include single-strand breaks or double-strand breaks.
In addition, SIRT6 promotes the repair of DNA double-strand breaks.
Non-homologous end joining ( NHEJ ) is a pathway that repairs double-strand breaks in DNA.
GT198 acts as a DNA repair factor responsible for error-free repair of DNA double-strand breaks.
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Examples of using Double-strand
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Double-strand polymers consist of uninterrupted chains of rings
They are additionally involved in repair of double-strand breaks
Double-strand breaks are especially threatening to bacterial viability
