Examples of 'strand breaks' in a sentence
Meaning of "strand breaks"
strand breaks ~ a term used in genetics and biology to describe the breaking of a DNA strand, which can lead to genetic mutations or disruptions in cellular processes
How to use "strand breaks" in a sentence
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strand breaks
Meiotic recombination is often initiated by double strand breaks.
The strand breaks accumulate and cell death follows.
Too low a viscosity can lead to strand breaks.
DNA strand breaks may occur vía the hydrolysis of labile alkylation sites.
As a result the strand breaks.
Double strand breaks can be introduced by meganucleases to raise the occurrence of Homologous Recombination.
Linear polymers frequently resonate immediately before the strand breaks.
Placement of double strand or single strand breaks relative to the target position.
Melt strength is indicated by the melt tension at which a molten strand breaks.
The assay is employed to label DNA strand breaks with TdT in each fragment.
The cells showed multiple damages including DNA strand breaks.
Transient DNA strand breaks in spermatids.
ATR is activated in response to single strand breaks.
Strand breaks in DNA were detected as follows.
Neutral DNA electrophoresis is thought to mainly detect double strand breaks.
See also
This leads to DNA strand breaks and inhibition of DNA synthesis.
Gamma irradiation acts directly on the chromosomes by causing DNA strand breaks.
The TUNEL method detects DNA strand breaks in cells undergoing apoptosis.
Mitomycin C and etoposide achieve cell death through a complex mechanism involving single strand breaks.
This UDG induction is coupled with DNA strand breaks and apoptotic signaling.
MX potentiation of TMZ is accompanied by a remarkable induction of DNA strand breaks.
It works by inducing DNA strand breaks and inhibiting incorporation of thymidine into DNA strand.
The comet assay is a method for measuring DNA strand breaks in eukaryotic cells.
In addition, DNA double strand breaks may initiate potentially damaging recombination events.
Analysis of chromatin dynamics during the repair of DNA double strand breaks in human cells.
After a DNA double strand breaks has occurred e . g.
Bleomycin acts by induction of DNA strand breaks.
Imexon-induced DNA single strand breaks were assessed by alkaline elution.
The Tdt enzyme binds to the free hydroxyl end of DNA strand breaks.
PARP aids in processing of DNA strand breaks induced during BER.
By contrast, cisplatin operates by a mechanism that ultimately induces double strand breaks.
Observed a PARP-dependent recovery of DNA strand breaks in leukocytes treated with hydrogen peroxide.
Type II topoisomerases catalyze DNA strand passage through transient double strand breaks in the DNA.
LIGASE DNA strand breaks and gaps are generated transiently during replication, repair and recombination.
Endo-exonuclease repairs double strand breaks.
Single strand breaks ( SSBs ) occur spontaneously in all cells.
Method as claimed in claim 2, wherein the target gene is involved in double strand breaks.
DNA damage usually involves single and double strand breaks in the sugar-phosphate backbone.
Chromosomal rearrangements, including translocations, require formation and joining of paired dna double strand breaks dsbs.
Cytotoxic DNA lesions include ICLs, DNA double strand breaks and transcription-blocking lesions.
In some embodiments, cell death is measured by DNA fragmentation or strand breaks.
The ZFN dimer creates targeted double strand breaks at exon 3 of IGF-1R.
Topoisomerase-I is a nuclear enzyme that relieves torsional strain in DNA by opening single strand breaks.
The presence of DNA strand breaks strongly activates PARP-1 and many studies reviewed in Pieper, A.
In general, any primary cell that is sensitive to double strand breaks may be used.
DNA strand breaks and other damage ( bone marrow, testes ) Unscheduled DNA synthesis ( testes ).
DNA damage can also comprise single or even double strand breaks e . g.
Most preferably, the first, seminal fluid comprises a substantial amount of spermatozoa with DNA strand breaks.
Bistriazenes are approximately 10-200 times more efficacious at producing strand breaks than dialkyltriazenes.
The exposed cells showed several forms of damage, including DNA strand breaks.
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